SCHEMBL19235036

SCHEMBL19235036

COc1cc(N=Nc2cc(OC)c(N=Nc3c(S(=O)(=O)O)cc4cc(Nc5ccccc5)ccc4c3O)cc2OC)c(OC)cc1N=Nc1ccc(O)c(C(=O)O)c1

nearest known ligand 0.70

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ PHLPP2 Q6ZVD8 4/20 0.70
▸ ENPP2 Q13822 10/20 0.66
▸ PRMT1 Q99873 2/20 0.51
▸ PRMT3 O60678 1/20 0.51
▸ EP300 Q09472 1/20 0.51
▸ PRMT6 Q96LA8 1/20 0.51
▸ CD40 P25942 1/20 0.49
▸ CD40LG P29965 1/20 0.49
▸ CARM1 Q86X55 1/20 0.44
▸ MEN1 O00255 1/20 0.43
▸ GAA P10253 1/20 0.43
▸ MAPT P10636 1/20 0.43
▸ KMT2A Q03164 1/20 0.43
▸ NPSR1 Q6W5P4 1/20 0.43
▸ L3MBTL1 Q9Y468 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19958170 0.98 PHLPP2 (0.67) PHLPP2ENPP2PRMT1PRMT3EP300
SCHEMBL19235035 0.89 ENPP2 (0.67) PHLPP2ENPP2PRMT1PRMT3EP300
SCHEMBL19235034 0.89 ENPP2 (0.66) PHLPP2ENPP2PRMT1PRMT3EP300
SCHEMBL19958172 0.88 ENPP2 (0.65) PHLPP2ENPP2PRMT1PRMT3EP300
SCHEMBL2615790 0.88 ENPP2 (0.71) PHLPP2ENPP2PRMT1PRMT3EP300
SCHEMBL17545735 0.88 ENPP2 (0.73) PHLPP2ENPP2PRMT1PRMT3EP300
SCHEMBL19235037 0.88 ENPP2 (0.73) PHLPP2ENPP2PRMT1PRMT3EP300
SCHEMBL19958169 0.87 ENPP2 (0.65) PHLPP2ENPP2PRMT1PRMT3EP300
SCHEMBL17515772 0.87 ENPP2 (0.65) PHLPP2ENPP2PRMT1PRMT3EP300
SCHEMBL19234785 0.86 ENPP2 (0.71) PHLPP2ENPP2PRMT1PRMT3EP300

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2017135391-A1 POLARIZER ELEMENT, AND POLARIZING PLATE AND DISPLAY DEVICE USING SAME 日本化薬株式会社 2017-08-10 — — WO disclosed
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