SCHEMBL19958169

SCHEMBL19958169

COc1cc(N=Nc2c(S(=O)(=O)O)cc3cc(Nc4ccccc4)ccc3c2O)c(O)cc1N=Nc1cc(C(=O)O)cc(C(=O)O)c1

nearest known ligand 0.65

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ ENPP2 Q13822 11/20 0.65
▸ PHLPP2 Q6ZVD8 3/20 0.53
▸ PRMT1 Q99873 2/20 0.50
▸ PRMT3 O60678 1/20 0.50
▸ EP300 Q09472 1/20 0.50
▸ PRMT6 Q96LA8 1/20 0.50
▸ CD40 P25942 1/20 0.46
▸ CD40LG P29965 1/20 0.46
▸ CARM1 Q86X55 1/20 0.43
▸ MEN1 O00255 1/20 0.39
▸ ALDH1A1 P00352 1/20 0.39
▸ MAPT P10636 1/20 0.39
▸ THRB P10828 1/20 0.39
▸ PKM P14618 1/20 0.39
▸ KMT2A Q03164 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19235034 0.97 ENPP2 (0.66) ENPP2PHLPP2PRMT1PRMT3EP300
SCHEMBL19958172 0.94 ENPP2 (0.65) ENPP2PHLPP2PRMT1PRMT3EP300
SCHEMBL19958209 0.91 ENPP2 (0.59) ENPP2PHLPP2PRMT1PRMT3EP300
SCHEMBL19235035 0.91 ENPP2 (0.67) ENPP2PHLPP2PRMT1PRMT3EP300
SCHEMBL15386682 0.90 ENPP2 (0.69) ENPP2PHLPP2PRMT1PRMT3EP300
SCHEMBL20735294 0.90 ENPP2 (0.65) ENPP2PHLPP2PRMT1PRMT3EP300
SCHEMBL19958170 0.90 PHLPP2 (0.67) ENPP2PHLPP2PRMT1PRMT3EP300
SCHEMBL19234936 0.90 ENPP2 (0.72) ENPP2PHLPP2PRMT1PRMT3EP300
SCHEMBL20747577 0.88 ENPP2 (0.63) ENPP2PHLPP2PRMT1PRMT3EP300
SCHEMBL19235036 0.87 PHLPP2 (0.70) ENPP2PHLPP2PRMT1PRMT3EP300

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10007142-B2 Dye-based polarizer as well as polarizing plate and liquid crystal display device using the polarizer NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2018-06-26 — — US disclosed
US-20180074371-A1 DYE-BASED POLARIZER AS WELL AS POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY DEVICE USING THE POLARIZER POLATECHNO CO., LTD. (JP) 2018-03-15 — — US disclosed
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