Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | PAOX | Q6QHF9 | 5/20 | 0.38 |
| ▸ | SCD | O00767 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
| ▸ | PPARA | Q07869 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10865900 | 0.86 | ALDH1A1 (0.38) | HDAC1ALDH1A1 | |
| SCHEMBL23692799 | 0.82 | HDAC1 (0.37) | HDAC1SCD | |
| SCHEMBL8242961 | 0.77 | HDAC1 (0.41) | HDAC1 | |
| SCHEMBL20825018 | 0.77 | HDAC1 (0.37) | HDAC1 | |
| SCHEMBL22268975 | 0.77 | ACHE (0.35) | HDAC1ALDH1A1 | |
| SCHEMBL23920955 | 0.77 | ACHE (0.35) | HDAC1ALDH1A1 | |
| SCHEMBL13896956 | 0.76 | CES1 (0.32) | HDAC1 | |
| SCHEMBL21499112 | 0.75 | HDAC1 (0.34) | HDAC1 | |
| SCHEMBL12831690 | 0.74 | NAMPT (0.30) | HDAC1 | |
| SCHEMBL20867336 | 0.73 | HDAC1 (0.36) | HDAC1PAOX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2906595-B1 | EXENDIN-4 DERIVATIVES AS DUAL GLP1/GLUCAGON AGONISTS | SANOFI SA (FR) | 2017-08-16 | — | — | EP | disclosed |