Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH3 | Q9ULD8 | 17/20 | 0.82 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1923802 | 0.92 | KCNH3 (0.88) | KCNH3 | |
| SCHEMBL1923404 | 0.91 | KCNH3 (0.98) | KCNH3SLC2A1 | |
| Hydrochloric Acid SCHEMBL3413499 | 0.90 | KCNH3 (1.00) | KCNH3SLC2A1 | |
| SCHEMBL1281719 | 0.90 | KCNH3 (0.97) | KCNH3 | |
| SCHEMBL5015531 | 0.89 | KCNH3 (0.78) | KCNH3SLC2A1MAPT | |
| Hydrochloric Acid SCHEMBL541197 | 0.89 | KCNH3 (1.00) | KCNH3 | |
| SCHEMBL5015077 | 0.88 | KCNH3 (0.82) | KCNH3KDM4ELMNAMAPTHTT | |
| SCHEMBL1924396 | 0.85 | KCNH3 (0.83) | KCNH3SLC2A1MAPT | |
| SCHEMBL1923916 | 0.84 | KCNH3 (0.97) | KCNH3 | |
| Hydrochloric Acid SCHEMBL3413936 | 0.83 | KCNH3 (1.00) | KCNH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1479397-B1 | 2,4,6-TRIAMINO-1,3,5-TRIAZINE DERIVATIVE | ASTELLAS PHARMA INC (JP) | 2011-06-08 | — | — | EP | claimed |
| US-7375222-B2 | 2,4,6-Triamino-1,3,5-triazine derivative | ASTELLAS PHARMA INC. (JP) | 2008-05-20 | — | — | US | claimed |