Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 12/20 | 0.62 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.62 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.60 |
| ▸ | MEN1 | O00255 | 3/20 | 0.60 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.60 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.60 |
| ▸ | DRD4 | P21917 | 3/20 | 0.60 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.60 |
| ▸ | HTR2B | P41595 | 3/20 | 0.60 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.60 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.60 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.60 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7510130 | 0.82 | DRD2 (0.59) | DRD2ADRA1AOPRM1MEN1ADRB2 | |
| SCHEMBL14307260 | 0.81 | CCR3 (0.69) | DRD2ADRA1AOPRM1SLC6A4HTR2B | |
| SCHEMBL20254427 | 0.80 | DRD2 (0.74) | DRD2ADRA1AOPRM1MEN1ADRB2 | |
| SCHEMBL10287607 | 0.80 | OPRM1 (0.63) | DRD2ADRA1AOPRM1SLC6A4HTR2B | |
| Chlorohaloperidol SCHEMBL4112719 | 0.76 | DRD2 (1.00) | DRD2ADRA1AOPRM1MEN1ADRB2 | |
| SCHEMBL11938907 | 0.76 | DRD2 (0.65) | DRD2ADRA1ASLC6A4HTR2BSLC6A3 | |
| SCHEMBL9051774 | 0.76 | DRD2 (1.00) | DRD2ADRA1AOPRM1MEN1ADRB2 | |
| Loperamide SCHEMBL8409779 | 0.76 | OPRM1 (1.00) | DRD2ADRA1AOPRM1MEN1ADRB2 | |
| Loperamide SCHEMBL28530 | 0.76 | OPRM1 (1.00) | DRD2ADRA1AOPRM1MEN1ADRB2 | |
| Loperamide SCHEMBL12387663 | 0.76 | OPRM1 (1.00) | DRD2ADRA1AOPRM1MEN1ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017133517-A1 | PHOSPHAMIDE DERIVATIVE, METHOD FOR MANUFACTURING THE SAME, AND USES THEREOF | 四川海思科制药有限公司 | 2017-08-10 | — | — | WO | disclosed |