SCHEMBL19237189

SCHEMBL19237189

C=Cc1ccc(-c2cc3sc(-c4ccc(C)cc4)cc3s2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 3/20 0.46
ESR2 Q92731 3/20 0.46
TP53 P04637 2/20 0.41
TDP1 Q9NUW8 2/20 0.41
ALDH1A1 P00352 2/20 0.39
MAPT P10636 3/20 0.37
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
STK17B O94768 1/20 0.36
CYP2A6 P11509 1/20 0.33
PKM P14618 1/20 0.33
NFE2L2 Q16236 1/20 0.33
RAB9A P51151 2/20 0.32
KDM4E B2RXH2 1/20 0.32
POLB P06746 1/20 0.32
RECQL P46063 1/20 0.32
MDM2 Q00987 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
NPC1 O15118 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13480644 0.85 ESR1 (0.49) ESR1ESR2MAPTNFE2L2KDM4E
SCHEMBL9968692 0.84 ESR1 (0.58) ESR1ESR2TP53TDP1ALDH1A1
SCHEMBL157101 0.78 ALDH1A1 (0.58) TP53TDP1ALDH1A1MAPTMEN1
SCHEMBL12422719 0.77 ESR1 (0.51) ESR1ESR2TDP1ALDH1A1KDM4E
SCHEMBL679555 0.76 ALDH1A1 (0.69) TP53TDP1ALDH1A1MAPTMEN1
SCHEMBL14911 0.76
SCHEMBL13480643 0.74 NFE2L2 (0.42) ESR1ESR2MAPTNFE2L2KDM4E
SCHEMBL13480649 0.74 ESR1 (0.57) ESR1ESR2MAPTNFE2L2KDM4E
Ethane SCHEMBL23051531 0.73 ALDH1A1 (0.65) TP53TDP1ALDH1A1MAPTMEN1
Ethylene SCHEMBL10713150 0.73 ALDH1A1 (0.65) TP53TDP1ALDH1A1MAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9825261-B2 Organic electroluminescent transistor FLEXTERRA, INC. (US) 2017-11-21 US disclosed
US-20170237043-A1 Organic Electroluminescent Transistor USINVEST LLC 2017-08-17 US disclosed