Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | PLAUR | Q03405 | 1/20 | 0.31 |
| ▸ | AHR | P35869 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.30 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.30 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16811498 | 0.94 | MAPT (0.34) | MAPK1MAPTTSHRNPSR1HSD17B10 | |
| SCHEMBL19769731 | 0.91 | KDM4E (0.36) | MAPK1MAPTTSHRNPSR1HSD17B10 | |
| SCHEMBL19239304 | 0.90 | KDM4E (0.37) | MAPK1MAPTTSHRNPSR1HSD17B10 | |
| SCHEMBL18593798 | 0.89 | MAPT (0.44) | MAPK1MAPTTSHRNPSR1HSD17B10 | |
| SCHEMBL16811708 | 0.88 | KDM4E (0.35) | MAPK1MAPTTSHRNPSR1HSD17B10 | |
| SCHEMBL16810928 | 0.87 | ALOX5 (0.37) | MAPK1MAPTTSHRNPSR1HSD17B10 | |
| SCHEMBL19129973 | 0.86 | MAPK1 (0.31) | MAPK1MAPTHPGDKMT2A | |
| SCHEMBL19787696 | 0.85 | MAPK1 (0.36) | MAPK1MAPTTSHRNPSR1HSD17B10 | |
| SCHEMBL16811014 | 0.85 | ALOX5 (0.38) | MAPK1MAPTTSHRNPSR1HSD17B10 | |
| SCHEMBL17245957 | 0.85 | MAPT (0.44) | MAPK1MAPTTSHRNPSR1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9876181-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2018-01-23 | — | — | US | disclosed |
| US-9876181-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2018-01-23 | — | — | US | disclosed |
| US-20170237017-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2017-08-17 | — | — | US | disclosed |
| US-20170237017-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2017-08-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170237017-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | DDT, ETFA, TST | MAPK1 3187/4885MAPT 543/4885TSHR 4442/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.