Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | CASP2 | P42575 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | NAAA | Q02083 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.40 |
| ▸ | KDM4A | O75164 | 1/20 | 0.40 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.40 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16689691 | 0.98 | ALDH1A1 (0.53) | ALDH1A1CASP2KMT2AMEN1LMNA | |
| SCHEMBL18768756 | 0.98 | ALDH1A1 (0.53) | ALDH1A1CASP2KMT2AMEN1LMNA | |
| SCHEMBL22851659 | 0.98 | ALDH1A1 (0.53) | ALDH1A1CASP2KMT2AMEN1LMNA | |
| SCHEMBL19239788 | 0.96 | ALDH1A1 (0.52) | ALDH1A1CASP2KMT2AMEN1LMNA | |
| SCHEMBL18313728 | 0.94 | ALDH1A1 (0.52) | ALDH1A1CASP2KMT2AMEN1LMNA | |
| SCHEMBL16248615 | 0.94 | ALDH1A1 (0.57) | ALDH1A1CASP2KMT2AMEN1LMNA | |
| SCHEMBL18513237 | 0.92 | ALDH1A1 (0.52) | ALDH1A1CASP2KMT2AMEN1LMNA | |
| SCHEMBL24818366 | 0.90 | NAMPT (0.52) | ALDH1A1CASP2KMT2AMEN1LMNA | |
| SCHEMBL10345306 | 0.90 | NAMPT (0.52) | ALDH1A1CASP2KMT2AMEN1LMNA | |
| SCHEMBL10660707 | 0.90 | NAMPT (0.52) | ALDH1A1CASP2KMT2AMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210139539-A1 | NEW ANTIBACTERIAL PRODUCTS | THE UNIVERSITY OF LIVERPOOL (GB) | 2021-05-13 | — | — | US | disclosed |
| US-20200407712-A1 | ARRAY-BASED CYCLIC PEPTIDE LIBRARIES | Cowper Sciences Inc. | 2020-12-31 | — | — | US | disclosed |
| US-20170233405-A1 | MAX BINDERS AS MYC MODULATORS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2017-08-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210139539-A1 | NEW ANTIBACTERIAL PRODUCTS | DBI, MRPL21, NRDC | ALDH1A1 1816/4885CASP2 870/4885KMT2A 4623/4885 |
| US-20170233405-A1 | MAX BINDERS AS MYC MODULATORS AND USES THEREOF | MYC, MYCBP, MYCBP2 | ALDH1A1 3226/4885CASP2 4465/4885KMT2A 1821/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.