Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.52 |
| ▸ | CASP2 | P42575 | 1/20 | 0.52 |
| ▸ | FAAH | O00519 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | NAAA | Q02083 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.46 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.46 |
| ▸ | KDM4A | O75164 | 1/20 | 0.46 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.46 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10345059 | 1.00 | NAMPT (0.52) | NAMPTCASP2FAAHLMNAPKM | |
| SCHEMBL10660707 | 1.00 | NAMPT (0.52) | NAMPTCASP2FAAHLMNAPKM | |
| SCHEMBL10345306 | 1.00 | NAMPT (0.52) | NAMPTCASP2FAAHLMNAPKM | |
| SCHEMBL19239788 | 0.94 | ALDH1A1 (0.52) | NAMPTCASP2FAAHLMNAPKM | |
| SCHEMBL23471810 | 0.94 | ALDH1A1 (0.50) | NAMPTCASP2FAAHLMNAPKM | |
| SCHEMBL425951 | 0.94 | ALDH1A1 (0.55) | NAMPTCASP2FAAHLMNAPKM | |
| SCHEMBL24810920 | 0.93 | CASP2 (0.65) | CASP2FAAHNAAADNM1CNR1 | |
| SCHEMBL24982632 | 0.93 | NAMPT (0.48) | NAMPTCASP2FAAHLMNAPKM | |
| SCHEMBL10345080 | 0.93 | CASP2 (0.65) | CASP2FAAHNAAADNM1CNR1 | |
| SCHEMBL10345070 | 0.93 | CASP2 (0.65) | CASP2FAAHNAAADNM1CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024138105-A1 | NOVEL RNA THERAPEUTICS AND USES THEREOF | ELI LILLY AND COMPANY (US) | 2024-06-27 | — | — | WO | disclosed |
| US-20230022590-A1 | NOVEL RNA THERAPEUTICS AND USES THEREOF | ELI LILLY AND COMPANY | 2023-01-26 | — | — | US | disclosed |
| WO-2022271808-A1 | NOVEL RNA THERAPEUTICS AND USES THEREOF | ELI LILLY AND COMPANY (US) | 2022-12-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230022590-A1 | NOVEL RNA THERAPEUTICS AND USES THEREOF | RNASE1, TEK, HDGFL3 | NAMPT 1007/4885CASP2 4223/4885FAAH 4037/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.