Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOS2 | Q07890 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NQO1 | P15559 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 2/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2960628 | 0.88 | SMN1; SMN2 (0.47) | HTR2AHTR2CSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL18183649 | 0.88 | KDM4E (0.44) | HTR2AHTR2CSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL29740385 | 0.88 | SMN1; SMN2 (0.47) | HTR2AHTR2CSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL4204764 | 0.83 | HTR2C (0.44) | HTR2AHTR2CHTR2B | |
| SCHEMBL21818701 | 0.77 | HTR2A (0.31) | SOS2HTR2AHTR2CHTR2B | |
| SCHEMBL12101153 | 0.77 | PNMT (0.49) | HTR2AHTR2CHTR2BSMN1; SMN2ADRA2A | |
| SCHEMBL31133318 | 0.77 | HTR2A (0.31) | SOS2HTR2AHTR2CHTR2B | |
| SCHEMBL3306895 | 0.75 | MAPT (0.44) | KDM4EALDH1A1LMNAMAPT | |
| SCHEMBL25432593 | 0.70 | TAS1R3 (0.35) | SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL31003080 | 0.68 | MAPT (0.33) | SOS2SMN1; SMN2NQO1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10865213-B2 | Max binders as MYC modulators and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2020-12-15 | — | — | US | disclosed |
| US-20190144466-A1 | MAX BINDERS AS MYC MODULATORS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2019-05-16 | — | — | US | disclosed |
| WO-2017143059-A1 | MAX BINDERS AS MYC MODULATORS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2017-08-24 | — | — | WO | disclosed |
| US-20170233405-A1 | MAX BINDERS AS MYC MODULATORS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2017-08-17 | — | — | US | disclosed |
| US-20170233405-A1 | MAX BINDERS AS MYC MODULATORS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2017-08-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170233405-A1 | MAX BINDERS AS MYC MODULATORS AND USES THEREOF | MYC, MYCBP, MYCBP2 | SOS2 2824/4885HTR2A 3947/4885HTR2C 4255/4885 |
| US-10865213-B2 | Max binders as MYC modulators and uses thereof | MYC, MYCBP, MYCBP2 | SOS2 2824/4885HTR2A 3947/4885HTR2C 4255/4885 |
| US-20190144466-A1 | MAX BINDERS AS MYC MODULATORS AND USES THEREOF | MYC, MYCBP, MYCBP2 | SOS2 2824/4885HTR2A 3947/4885HTR2C 4255/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.