Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAD52 | P43351 | 1/20 | 0.50 |
| ▸ | IDO1 | P14902 | 1/20 | 0.48 |
| ▸ | BAX | Q07812 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 2/20 | 0.36 |
| ▸ | DRD3 | P35462 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17084302 | 0.93 | RAD52 (0.45) | RAD52IDO1BAXTP53CYP3A4 | |
| SCHEMBL12402904 | 0.92 | RAD52 (0.56) | RAD52IDO1BAXTP53CYP3A4 | |
| SCHEMBL2800007 | 0.85 | SMN1; SMN2 (0.58) | RAD52IDO1BAXTP53CYP3A4 | |
| SCHEMBL24319375 | 0.85 | SMN1; SMN2 (0.58) | RAD52IDO1BAXTP53CYP3A4 | |
| SCHEMBL17934826 | 0.85 | SMN1; SMN2 (0.58) | RAD52IDO1BAXTP53CYP3A4 | |
| SCHEMBL17084303 | 0.80 | POLB (0.41) | RAD52IDO1BAXTP53CYP3A4 | |
| SCHEMBL3356828 | 0.79 | CSNK2A1 (0.39) | SLC18A3 | |
| SCHEMBL21250355 | 0.77 | RAD52 (0.41) | RAD52IDO1BAXTP53CYP3A4 | |
| SCHEMBL18661602 | 0.77 | RAD52 (0.41) | RAD52IDO1BAXTP53CYP3A4 | |
| SCHEMBL11438133 | 0.77 | SMN1; SMN2 (0.60) | RAD52IDO1BAXTP53CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170233598-A1 | TRAFFIC MARKING COMPOSITIONS CONTAINING POLYFUNCTIONAL AMINES | ENNIS-FLINT, INC. | 2017-08-17 | — | — | US | disclosed |
| US-20150307465-A1 | Iminothiadiazine Dioxide Compounds as BACE Inhibitors, Compositions and Their Use | MERCK SHARP & DOHME CORP. (US) | 2015-10-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150307465-A1 | Iminothiadiazine Dioxide Compounds as BACE Inhibitors, Compositions and Their Use | BACE1, BACE2, APP | RAD52 2728/4885IDO1 456/4885BAX 1081/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.