Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | TYK2 | P29597 | 6/20 | 0.53 |
| ▸ | JAK2 | O60674 | 6/20 | 0.53 |
| ▸ | JAK1 | P23458 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.51 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | PDE4A | P27815 | 1/20 | 0.49 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.49 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.49 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | PRKCI | P41743 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27195662 | 0.76 | KDM4E (0.56) | KDM4EL3MBTL1TYK2JAK2JAK1 | |
| SCHEMBL8556169 | 0.75 | DEGS1 (0.69) | KDM4ETYK2JAK2HTTNPC1 | |
| SCHEMBL23112987 | 0.75 | DEGS1 (0.49) | KDM4ENPC1RAB9AKMT2AALDH1A1 | |
| SCHEMBL29837345 | 0.75 | DEGS1 (0.49) | KDM4ENPC1RAB9AKMT2AALDH1A1 | |
| SCHEMBL27946675 | 0.74 | JAK2 (0.77) | KDM4EL3MBTL1TYK2JAK2HTT | |
| SCHEMBL19774580 | 0.72 | KDM4E (0.67) | KDM4EL3MBTL1TYK2JAK2JAK1 | |
| SCHEMBL31171356 | 0.72 | TYK2 (0.58) | KDM4EL3MBTL1TYK2JAK2JAK1 | |
| SCHEMBL30828550 | 0.70 | KDM4E (0.87) | KDM4EL3MBTL1TYK2JAK2HTT | |
| SCHEMBL1898755 | 0.70 | GAA (0.91) | KDM4EL3MBTL1TYK2JAK2HTT | |
| SCHEMBL14716526 | 0.70 | KDM4E (1.00) | KDM4EL3MBTL1TYK2JAK2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3411140-B1 | METHOD FOR SEPARATING ACETYLENE FROM A GAS MIXTURE | UNIV LIMERICK (IE) | 2021-08-18 | — | — | EP | disclosed |
| EP-3500582-B1 | POROUS CHIRAL MATERIALS AND USES THEREOF | UNIV NANKAI (CN) | 2021-08-11 | — | — | EP | disclosed |
| US-11058985-B2 | Methods for gas separation | UNIVERSITY OF LIMERICK (IE) | 2021-07-13 | — | — | US | disclosed |
| EP-3791949-A1 | IMPROVEMENTS RELATING TO GAS SEPARATION | University of Limerick (IE) | 2021-03-17 | — | — | EP | disclosed |
| US-10857517-B2 | Porous chiral materials and uses thereof | NANKAI UNIVERSITY (CN) | 2020-12-08 | — | — | US | disclosed |
| US-20190054413-A1 | METHODS FOR GAS SEPARATION | THE UNIVERSITY OF LIMERICK (IE) | 2019-02-21 | — | — | US | disclosed |
| WO-2017132816-A1 | METHODS FOR GAS SEPARATION | UNIVERSITY OF LIMERICK (IE) | 2017-08-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10857517-B2 | Porous chiral materials and uses thereof | ANXA7, XDH, OPRM1 | KDM4E 3822/4885L3MBTL1 555/4885TYK2 3732/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.