SCHEMBL19243000

SCHEMBL19243000

CCC(C)c1c(OC)cc(OC)cc1OC

nearest known ligand 0.48

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.40
CA12 O43570 1/20 0.40
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40
CA7 P43166 1/20 0.40
CA9 Q16790 1/20 0.40
CA14 Q9ULX7 1/20 0.40
MAPT P10636 2/20 0.39
GAA P10253 1/20 0.39
LMNA P02545 1/20 0.39
TP53 P04637 1/20 0.39
ALOX12 P18054 1/20 0.39
CYP1A2 P05177 2/20 0.38
CYP1A1 P04798 1/20 0.38
CYP1B1 Q16678 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25275373 0.82 CA12 (0.39) ALDH1A1CA12CA1CA2CA7
SCHEMBL16617685 0.79 ABCB11 (0.38) ALDH1A1CA12CA1CA2CA7
SCHEMBL11983792 0.78 ALDH1A1 (0.48) ALDH1A1CA12CA1CA2CA7
SCHEMBL20148897 0.78 ALDH1A1 (0.48) ALDH1A1CA12CA1CA2CA7
SCHEMBL28054406 0.77 ALDH1A1 (0.47) ALDH1A1MAPTLMNA
SCHEMBL5471180 0.77 CA1 (0.44) ALDH1A1CA12CA1CA2CA7
SCHEMBL10208048 0.76 TUBB1 (0.53) CYP1A2CYP1A1CYP1B1
SCHEMBL21166499 0.76 CYP2D6 (0.37) ALDH1A1MAPTGAALMNA
SCHEMBL5998927 0.75 ALDH1A1 (0.50) ALDH1A1CA12CA1CA2CA7
SCHEMBL12606793 0.75 CA12 (0.50) ALDH1A1CA12CA1CA2CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2017139689-A1 DERIVATIVES OF BODIPY OREGON HEALTH & SCIENCE UNIVERSITY (US) 2017-08-17 WO disclosed