Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGK1 | P00558 | 1/20 | 0.35 |
| ▸ | PGK2 | P07205 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.32 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.32 |
| ▸ | NR1H2 | P55055 | 4/20 | 0.32 |
| ▸ | NR1H3 | Q13133 | 4/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15169777 | 0.86 | OPRL1 (0.43) | OPRM1OPRL1 | |
| SCHEMBL15229301 | 0.84 | OPRK1 (0.41) | KDM4EGAAOPRM1 | |
| SCHEMBL382057 | 0.84 | ACP3 (0.43) | RIPK1OPRM1OPRL1 | |
| SCHEMBL381185 | 0.84 | ACP3 (0.47) | ATMGAA | |
| SCHEMBL15170368 | 0.84 | ACP3 (0.47) | ATMGAA | |
| SCHEMBL19305426 | 0.84 | RIPK1 (0.42) | RIPK1KDM4EATMNR1H2NR1H3 | |
| SCHEMBL19305428 | 0.84 | RIPK1 (0.42) | RIPK1KDM4EATMNR1H2NR1H3 | |
| SCHEMBL531655 | 0.84 | RIPK1 (0.42) | RIPK1KDM4EATMNR1H2NR1H3 | |
| SCHEMBL17686018 | 0.77 | MEN1 (0.40) | RIPK1OPRM1OPRL1 | |
| SCHEMBL3340453 | 0.77 | TDP1 (0.38) | RIPK1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2408751-B1 | Substituted 2-acetamido-5-aryl-1,2,4-triazolones and use thereof | BAYER IP GMBH (DE) | 2017-08-23 | — | — | EP | disclosed |