SCHEMBL1924615

SCHEMBL1924615

C/C(=C/C#N)CCc1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 1/20 0.50
▸ KEAP1 Q14145 1/20 0.44
▸ FFAR1 O14842 1/20 0.41
▸ TRPV1 Q8NER1 2/20 0.39
▸ KDM4E B2RXH2 2/20 0.39
▸ RECQL P46063 1/20 0.39
▸ TDP1 Q9NUW8 3/20 0.39
▸ HDAC2 Q92769 2/20 0.39
▸ HDAC8 Q9BY41 2/20 0.39
▸ HDAC6 Q9UBN7 2/20 0.39
▸ KMT2A Q03164 2/20 0.39
▸ GPR52 Q9Y2T5 1/20 0.39
▸ L3MBTL1 Q9Y468 1/20 0.38
▸ HDAC3 O15379 1/20 0.37
▸ MAPK1 P28482 1/20 0.37
▸ ADRA1A P35348 1/20 0.37
▸ HDAC4 P56524 1/20 0.37
▸ SLC6A3 Q01959 1/20 0.37
▸ HDAC1 Q13547 1/20 0.37
▸ SMN1; SMN2 Q16637 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL111450 1.00 ALDH1A1 (0.50) ALDH1A1KEAP1FFAR1TRPV1KDM4E
SCHEMBL17629448 1.00 ALDH1A1 (0.50) ALDH1A1KEAP1FFAR1TRPV1KDM4E
SCHEMBL111451 1.00 ALDH1A1 (0.50) ALDH1A1KEAP1FFAR1TRPV1KDM4E
SCHEMBL6457350 0.88 MAPT (0.47) ALDH1A1HDAC2HDAC8HDAC6L3MBTL1
SCHEMBL6457353 0.88 MAPT (0.47) ALDH1A1HDAC2HDAC8HDAC6L3MBTL1
SCHEMBL11437178 0.84 FFAR1 (0.44) ALDH1A1FFAR1TDP1L3MBTL1
SCHEMBL11444196 0.84 CYP2A6 (0.42) ALDH1A1FFAR1KDM4EKMT2AL3MBTL1
SCHEMBL11444236 0.84 LPL (0.40) ALDH1A1KDM4EKMT2AL3MBTL1
SCHEMBL11451056 0.84 LPL (0.40) ALDH1A1KDM4EKMT2AL3MBTL1
SCHEMBL11442008 0.84 CYP2A6 (0.42) ALDH1A1FFAR1KDM4EKMT2AL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 108 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025051371-A1 A FRAGRANCE PASTILLE SYMRISE AG (DE) 2025-03-13 — — WO claimed
WO-2025045353-A1 A FRAGRANCE POD SYMRISE AG (DE) 2025-03-06 — — WO claimed
WO-2025045354-A1 A FRAGRANCE TABLET SYMRISE AG (DE) 2025-03-06 — — WO claimed
EP-4438065-A2 A MIXTURE COMPRISING 1,2-ALKANEDIOLS Symrise AG (DE) 2024-10-02 — — EP claimed
CN-110099993-B High impact perfume microcapsules of balanced density 弗门尼舍有限公司 2021-08-24 — — CN claimed
US-10918579-B2 Density balanced high impact perfume microcapsules FIRMENICH SA (CH) 2021-02-16 — — US claimed
US-20190155975-A9 Antiperspirant and Deodorant Compositions Comprising Malodor Reduction Compositions THE PROCTER & GAMBLE COMPANY 2019-05-23 — — US claimed
US-10240108-B2 Particles for malodor reduction THE PROCTER & GAMBLE COMPANY (US) 2019-03-26 — — US claimed
EP-3365418-A2 PARTICLES FOR MALODOR REDUCTION The Procter and Gamble Company (US) 2018-08-29 — — EP claimed
US-20180004875-A1 Antiperspirant and Deodorant Compositions Comprising Malodor Reduction Compositions THE PROCTER & GAMBLE COMPANY 2018-01-04 — — US claimed
WO-2016049398-A1 FRESHENING COMPOSITIONS AND DEVICES COMPRISING SAME THE PROCTER & GAMBLE COMPANY (US) 2016-03-31 — — WO claimed
WO-2016049396-A1 ANTIPERSPIRANT AND DEODORANT COMPOSITIONS COMPRISING MALODOR REDUCTION COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 2016-03-31 — — WO claimed
WO-2016049389-A1 MALODOR REDUCTION COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 2016-03-31 — — WO claimed
US-20160090556-A1 PRODUCTS COMPRISING MALODOR REDUCTION MATERIALS THE PROCTER & GAMBLE COMPANY 2016-03-31 — — US claimed
WO-2016049458-A1 DELIVERY SYSTEMS COMPRISING MALODOR REDUCTION COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 2016-03-31 — — WO claimed
WO-2016049407-A1 ABSORBENT ARTICLE COMPRISING MALODOR REDUCTION COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 2016-03-31 — — WO claimed
WO-2016049455-A1 PERSONAL CARE COMPOSITIONS COMPRISING MALODOR REDUCTION COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 2016-03-31 — — WO claimed
WO-2016049394-A1 CLEANING AND/OR TREATMENT COMPOSITIONS COMPRISING MALODOR REDUCTION COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 2016-03-31 — — WO claimed
US-20160089464-A1 MALODOR REDUCTION COMPOSITIONS THE PROCTER & GAMBLE COMPANY 2016-03-31 — — US claimed
US-4193934-A PERFUMES HAARMANN & REIMER GMBH (DE) 1980-03-18 — — US claimed
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