Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | GMNN | O75496 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | THPO | P40225 | 1/20 | 0.50 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.50 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2464249 | 0.77 | HTT (0.50) | SMN1; SMN2ALDH1A1LMNAHDAC3HDAC1 | |
| Hydrochloric Acid SCHEMBL11830306 | 0.75 | HTT (0.49) | SMN1; SMN2ALDH1A1LMNAHDAC3HDAC1 | |
| SCHEMBL20268246 | 0.75 | HTT (0.51) | SMN1; SMN2ALDH1A1LMNAHDAC3HDAC1 | |
| SCHEMBL6425135 | 0.74 | CNR2 (0.52) | SMN1; SMN2MAPTALDH1A1HSD17B10CNR2 | |
| SCHEMBL10102854 | 0.73 | CCR5 (0.60) | SMN1; SMN2MAPTALDH1A1LMNAEPHX2 | |
| SCHEMBL7101616 | 0.73 | FFAR4 (0.60) | SMN1; SMN2EPHX2FFAR4HDAC3MAPK1 | |
| SCHEMBL19265536 | 0.72 | CNR2 (0.50) | SMN1; SMN2MAPTALDH1A1CNR2EPHX1 | |
| SCHEMBL2259800 | 0.72 | HTT (0.51) | SMN1; SMN2ALDH1A1LMNAHPGD | |
| SCHEMBL6208836 | 0.71 | SMN1; SMN2 (0.82) | SMN1; SMN2CYP2D6MAPTALDH1A1GMNN | |
| SCHEMBL2356277 | 0.69 | SMN1; SMN2 (0.51) | SMN1; SMN2CYP2D6MAPTALDH1A1GMNN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2409569-B1 | Method for administering GLP-1 molecules | EMISPHERE TECH INC (US) | 2017-08-16 | — | — | EP | disclosed |