Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDO2 | P48775 | 16/20 | 0.64 |
| ▸ | IDO1 | P14902 | 9/20 | 0.56 |
| ▸ | MET | P08581 | 3/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19249008 | 0.87 | TDO2 (0.74) | TDO2IDO1 | |
| SCHEMBL22083897 | 0.86 | TDO2 (0.56) | TDO2IDO1 | |
| SCHEMBL19249092 | 0.79 | TDO2 (1.00) | TDO2IDO1 | |
| SCHEMBL19249005 | 0.78 | TDO2 (1.00) | TDO2IDO1METKCNH2 | |
| SCHEMBL19249003 | 0.78 | TDO2 (1.00) | TDO2IDO1METKCNH2 | |
| SCHEMBL19249225 | 0.76 | TDO2 (1.00) | TDO2IDO1MET | |
| SCHEMBL19249224 | 0.74 | TDO2 (1.00) | TDO2IDO1MET | |
| SCHEMBL696485 | 0.73 | IDH1 (0.62) | — | |
| SCHEMBL22083901 | 0.73 | TDO2 (0.62) | TDO2IDO1 | |
| SCHEMBL19249227 | 0.72 | TDO2 (0.61) | TDO2IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017133258-A1 | 1H-INDAZOLE DERIVATIVE AND USE THEREOF AS IDO INHIBITOR | 西华大学 | 2017-08-10 | — | — | WO | disclosed |