Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | NAAA | Q02083 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19239816 | 0.82 | TDP1 (0.39) | KMT2AHTR2CALDH1A1MAPTTHRB | |
| SCHEMBL12200861 | 0.81 | DGKA (0.44) | HTR2CALDH1A1MAPTTHRBCNR1 | |
| SCHEMBL28491967 | 0.80 | NAAA (0.47) | HTR2CALDH1A1MAPTTHRBCNR1 | |
| SCHEMBL8862596 | 0.79 | NAAA (0.46) | HTR2CALDH1A1TDP1NAAATSHR | |
| SCHEMBL5690086 | 0.78 | CYP1A2 (0.48) | KMT2AALDH1A1THRBTDP1CYP1A2 | |
| SCHEMBL1904557 | 0.78 | CYP1A2 (0.48) | KMT2AALDH1A1THRBTDP1CYP1A2 | |
| SCHEMBL17947433 | 0.78 | CYP1A2 (0.48) | KMT2AALDH1A1THRBTDP1CYP1A2 | |
| SCHEMBL12092171 | 0.77 | TSHR (0.39) | KMT2ATDP1TSHRMEN1 | |
| SCHEMBL16543622 | 0.77 | TSHR (0.39) | KMT2ATDP1TSHRMEN1 | |
| SCHEMBL9526687 | 0.77 | TSHR (0.39) | KMT2ATDP1TSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10865213-B2 | Max binders as MYC modulators and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2020-12-15 | — | — | US | disclosed |
| US-20190144466-A1 | MAX BINDERS AS MYC MODULATORS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2019-05-16 | — | — | US | disclosed |
| US-20170233405-A1 | MAX BINDERS AS MYC MODULATORS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2017-08-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170233405-A1 | MAX BINDERS AS MYC MODULATORS AND USES THEREOF | MYC, MYCBP, MYCBP2 | CA2 3803/4885KMT2A 1821/4885HTR2C 4255/4885 |
| US-10865213-B2 | Max binders as MYC modulators and uses thereof | MYC, MYCBP, MYCBP2 | CA2 3803/4885KMT2A 1821/4885HTR2C 4255/4885 |
| US-20190144466-A1 | MAX BINDERS AS MYC MODULATORS AND USES THEREOF | MYC, MYCBP, MYCBP2 | CA2 3803/4885KMT2A 1821/4885HTR2C 4255/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.