Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDO2 | P48775 | 2/20 | 0.34 |
| ▸ | MET | P08581 | 4/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.32 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.32 |
| ▸ | TEAD1 | P28347 | 2/20 | 0.31 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | DDR2 | Q16832 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19249350 | 0.84 | MRGPRX4 (0.36) | TDO2METRXFP1ROCK2ROCK1 | |
| SCHEMBL19249229 | 0.77 | TDO2 (0.60) | TDO2ROCK2ROCK1 | |
| SCHEMBL19249094 | 0.76 | TDO2 (0.50) | TDO2RXFP1ROCK2ROCK1EGFR | |
| SCHEMBL3670657 | 0.73 | EPHX2 (0.51) | ALDH1A1TEAD1 | |
| SCHEMBL22083868 | 0.71 | CDK7 (0.34) | ROCK2KCNH2 | |
| SCHEMBL22083864 | 0.66 | TDO2 (0.54) | TDO2 | |
| SCHEMBL19249227 | 0.63 | TDO2 (0.61) | TDO2ROCK2ROCK1 | |
| SCHEMBL3668555 | 0.61 | DDB1 (0.42) | ALDH1A1 | |
| SCHEMBL22083903 | 0.60 | KIF11 (0.41) | RXFP1ALDH1A1 | |
| SCHEMBL19249228 | 0.58 | PTPN5 (0.42) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017133258-A1 | 1H-INDAZOLE DERIVATIVE AND USE THEREOF AS IDO INHIBITOR | 西华大学 | 2017-08-10 | — | — | WO | disclosed |