Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GMPS | P49915 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17256253 | 0.77 | TSHR (0.41) | TSHR | |
| SCHEMBL18227311 | 0.75 | TSHR (0.36) | TSHRKDM4E | |
| SCHEMBL19249813 | 0.72 | TSHR (0.42) | L3MBTL1HDAC3HDAC2HDAC8NCOR2 | |
| SCHEMBL19610499 | 0.71 | TSHR (0.33) | ALDH1A1TSHR | |
| SCHEMBL17268906 | 0.70 | CTSK (0.35) | TSHR | |
| SCHEMBL13301163 | 0.69 | NPC1 (0.47) | HTTNPC1KDM4E | |
| SCHEMBL20386871 | 0.68 | TSHR (0.35) | TSHR | |
| SCHEMBL19153446 | 0.68 | KDM4E (0.35) | TSHRKDM4E | |
| SCHEMBL19249812 | 0.68 | HRH3 (0.40) | L3MBTL1ALDH1A1TSHR | |
| SCHEMBL21291238 | 0.68 | TSHR (0.53) | L3MBTL1ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017137895-A1 | NEW DENDRIMERIC PYRROLIDINES, THEIR SYNTHESIS AND MEDICAL USE | UNIVERSITA' DEGLI STUDI DI FIRENZE (IT) | 2017-08-17 | — | — | WO | disclosed |