SCHEMBL19610499

SCHEMBL19610499

C#CCOCC(COCC#C)(COCC#C)NC(=O)C=C

nearest known ligand 0.33

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.33
ALDH1A1 P00352 2/20 0.32
MAPK1 P28482 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
CYP3A4 P08684 1/20 0.31
CYP2C9 P11712 1/20 0.31
CYP2C19 P33261 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21236784 0.92
SCHEMBL19622520 0.92
SCHEMBL19622521 0.92 ALDH1A1 (0.31) ALDH1A1CYP3A4CYP2C9CYP2C19
SCHEMBL18240012 0.83 ALDH1A1 (0.36) TSHRALDH1A1MAPK1TDP1CYP3A4
SCHEMBL17256253 0.78 TSHR (0.41) TSHR
SCHEMBL23097495 0.77 ALDH1A1 (0.32) ALDH1A1CYP3A4CYP2C9CYP2C19
SCHEMBL18227311 0.77 TSHR (0.36) TSHR
SCHEMBL15222116 0.75 ALDH1A1 (0.43) TSHRALDH1A1MAPK1TDP1CYP3A4
SCHEMBL19249813 0.74 TSHR (0.42) TSHRALDH1A1
SCHEMBL20220733 0.73 ZDHHC20 (0.39) TSHRALDH1A1MAPK1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3246353-B1 USE OF SURFACTANTS TO EXTRACT A PLATINUM GROUP METAL OR GOLD FROM ORGANIC COMPOSITIONS CENTRE NAT RECH SCIENT (FR) 2021-03-17 EP disclosed
EP-3246353-B1 USE OF SURFACTANTS TO EXTRACT A PLATINUM GROUP METAL OR GOLD FROM ORGANIC COMPOSITIONS CENTRE NAT RECH SCIENT (FR) 2021-03-17 EP disclosed
US-10752976-B2 Process of extraction of a platinum group metal or gold from organic compositions with surfactants UNIVERSITE DE STRASBOURG (FR) 2020-08-25 US disclosed
US-10752976-B2 Process of extraction of a platinum group metal or gold from organic compositions with surfactants UNIVERSITE DE STRASBOURG (FR) 2020-08-25 US disclosed
US-20190316223-A1 Use of Surfactants to Extract a Platinum Group Metal or Gold from Organic Compositions CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2019-10-17 US disclosed
US-20190316223-A1 Use of Surfactants to Extract a Platinum Group Metal or Gold from Organic Compositions CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2019-10-17 US disclosed
EP-3298066-B1 DENDRI-TAC AND THEIR USE AS THERANOSTICS UNIV D'AVIGNON ET DES PAYS DE VAUCLUSE (FR) 2019-08-07 EP disclosed
EP-3298066-B1 DENDRI-TAC AND THEIR USE AS THERANOSTICS UNIV D'AVIGNON ET DES PAYS DE VAUCLUSE (FR) 2019-08-07 EP disclosed
US-10286091-B2 Dendri-TAC and their use as theranostics UNIVERSITE D'AVIGNON ET DES PAYS DU VAUCLUSE (FR) 2019-05-14 US disclosed
US-10286091-B2 Dendri-TAC and their use as theranostics UNIVERSITE D'AVIGNON ET DES PAYS DU VAUCLUSE (FR) 2019-05-14 US disclosed
EP-3458501-A1 USE OF SURFACTANTS TO EXTRACT A PLATINUM GROUP METAL OR GOLD FROM ORGANIC COMPOSITIONS Centre National De La Recherche Scientifique (FR) 2019-03-27 EP disclosed
US-20180126011-A1 DENDRI-TAC AND THEIR USE AS THERANOSTICS CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2018-05-10 US disclosed
US-20180126011-A1 DENDRI-TAC AND THEIR USE AS THERANOSTICS CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2018-05-10 US disclosed
US-20180126011-A1 DENDRI-TAC AND THEIR USE AS THERANOSTICS CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2018-05-10 US disclosed
WO-2017198846-A1 USE OF SURFACTANTS TO EXTRACT A PLATINUM GROUP METAL OR GOLD FROM ORGANIC COMPOSITIONS CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2017-11-23 WO disclosed
WO-2017198846-A1 USE OF SURFACTANTS TO EXTRACT A PLATINUM GROUP METAL OR GOLD FROM ORGANIC COMPOSITIONS CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2017-11-23 WO disclosed
EP-3246353-A1 USE OF SURFACTANTS TO EXTRACT A PLATINUM GROUP METAL OR GOLD FROM ORGANIC COMPOSITIONS Centre National De La Recherche Scientifique (FR) 2017-11-22 EP disclosed
EP-3246353-A1 USE OF SURFACTANTS TO EXTRACT A PLATINUM GROUP METAL OR GOLD FROM ORGANIC COMPOSITIONS Centre National De La Recherche Scientifique (FR) 2017-11-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180126011-A1 DENDRI-TAC AND THEIR USE AS THERANOSTICS DBI, CDIPT, DGKI TSHR 973/4885ALDH1A1 2512/4885MAPK1 4821/4885
US-10286091-B2 Dendri-TAC and their use as theranostics DBI, CDIPT, DGKI TSHR 973/4885ALDH1A1 2512/4885MAPK1 4821/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.