Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDO2 | P48775 | 20/20 | 0.52 |
| ▸ | IDO1 | P14902 | 18/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22083948 | 0.82 | TDO2 (0.45) | TDO2IDO1CYP2C9 | |
| SCHEMBL22083892 | 0.79 | TDO2 (0.46) | TDO2IDO1CYP2C9 | |
| SCHEMBL28457353 | 0.76 | TDO2 (0.59) | TDO2IDO1CYP2C9 | |
| SCHEMBL19249344 | 0.72 | TDO2 (0.51) | TDO2IDO1CYP2C9 | |
| SCHEMBL28451986 | 0.71 | TDO2 (0.55) | TDO2IDO1CYP2C9 | |
| SCHEMBL28451309 | 0.71 | TDO2 (0.52) | TDO2IDO1CYP2C9 | |
| SCHEMBL28673212 | 0.68 | TDO2 (1.00) | TDO2IDO1CYP2C9 | |
| SCHEMBL28449820 | 0.68 | TDO2 (1.00) | TDO2IDO1CYP2C9 | |
| SCHEMBL28447373 | 0.67 | IDO1 (0.50) | TDO2IDO1CYP2C9 | |
| SCHEMBL16935415 | 0.66 | TDO2 (0.45) | TDO2IDO1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017133258-A1 | 1H-INDAZOLE DERIVATIVE AND USE THEREOF AS IDO INHIBITOR | 西华大学 | 2017-08-10 | — | — | WO | disclosed |