Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDO2 | P48775 | 19/20 | 0.55 |
| ▸ | IDO1 | P14902 | 18/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19249344 | 0.88 | TDO2 (0.51) | TDO2IDO1CYP2C9 | |
| SCHEMBL28447373 | 0.86 | IDO1 (0.50) | TDO2IDO1CYP2C9 | |
| SCHEMBL19249343 | 0.82 | TDO2 (0.74) | TDO2IDO1CYP2C9 | |
| SCHEMBL19248997 | 0.80 | NPC1 (0.52) | TDO2IDO1 | |
| SCHEMBL28457353 | 0.80 | TDO2 (0.59) | TDO2IDO1CYP2C9 | |
| SCHEMBL28451310 | 0.78 | TDO2 (0.64) | TDO2IDO1CYP2C9 | |
| SCHEMBL19248990 | 0.75 | TDO2 (0.72) | TDO2IDO1 | |
| SCHEMBL22083965 | 0.75 | TDO2 (0.69) | TDO2IDO1CYP2C9 | |
| SCHEMBL28451309 | 0.71 | TDO2 (0.52) | TDO2IDO1CYP2C9 | |
| SCHEMBL19249342 | 0.71 | TDO2 (0.52) | TDO2IDO1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107033087-B | 1H-indazole-4-amine compounds and use thereof as IDO inhibitors | 西华大学 | 2020-09-04 | — | — | CN | disclosed |