Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.34 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.34 |
| ▸ | LATS1 | O95835 | 4/20 | 0.31 |
| ▸ | NAMPT | P43490 | 1/20 | 0.31 |
| ▸ | LATS2 | Q9NRM7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19249406 | 0.87 | LOXL2 (0.42) | PTGDR2 | |
| SCHEMBL19249487 | 0.86 | PTGDR2 (0.35) | PTGDR2 | |
| SCHEMBL19249957 | 0.86 | LOXL2 (0.39) | PTGDR2 | |
| SCHEMBL19249475 | 0.81 | BRD4 (0.31) | — | |
| SCHEMBL20915555 | 0.76 | LOXL2 (0.46) | PTGDR2 | |
| SCHEMBL20915553 | 0.76 | LOXL2 (0.46) | PTGDR2 | |
| SCHEMBL19255180 | 0.74 | LOXL2 (0.41) | — | |
| SCHEMBL19255103 | 0.74 | LOXL2 (0.40) | — | |
| SCHEMBL19249895 | 0.74 | CYP2D6 (0.36) | PTGDR2 | |
| SCHEMBL20915620 | 0.73 | LOXL2 (0.51) | PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017136871-A9 | INDOLE AND AZAINDOLE HALOALLYLAMINE DERIVATIVE INHIBITORS OF LYSYL OXIDASES AND USES THEREOF | PHARMAXIS LTD. (AU) | 2018-02-15 | — | — | WO | disclosed |
| WO-2017136871-A1 | INDOLE AND AZAINDOLE HALOALLYLAMINE DERIVATIVE INHIBITORS OF LYSYL OXIDASES AND USES THEREOF | PHARMAXIS LTD. (AU) | 2017-08-17 | — | — | WO | disclosed |