Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | PPM1B | O75688 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | ANPEP | P15144 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8761201 | 0.93 | PPM1B (0.38) | CHRM2CHRM4CHRM3PPM1BPTPN1 | |
| SCHEMBL8760662 | 0.93 | PPM1B (0.38) | CHRM2CHRM4CHRM3PPM1BPTPN1 | |
| SCHEMBL7354850 | 0.80 | PPM1B (0.45) | CHRM2CHRM4CHRM3PPM1BPTPN1 | |
| SCHEMBL16448666 | 0.80 | PPM1B (0.45) | CHRM2CHRM4CHRM3PPM1BPTPN1 | |
| SCHEMBL14357849 | 0.79 | CHRM2 (0.42) | CHRM2CHRM4CHRM3PPM1BPTPN1 | |
| SCHEMBL30933030 | 0.76 | PPM1B (0.45) | CHRM2CHRM4CHRM3PPM1BPTPN1 | |
| SCHEMBL6551846 | 0.76 | PPM1B (0.45) | CHRM2CHRM4CHRM3PPM1BPTPN1 | |
| SCHEMBL14828638 | 0.75 | CHRNB2 (0.33) | PPM1BPTPN1PPP1CCMMP2ANPEP | |
| SCHEMBL24404660 | 0.74 | PPM1B (0.42) | PPM1BPTPN1PPP1CCCYP2C19MEN1 | |
| SCHEMBL30417584 | 0.74 | PPM1B (0.42) | PPM1BPTPN1PPP1CCALOX15TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017133667-A1 | PYRIMIDINE AND PYRIDINE DERIVATIVES AND USE IN TREATMENT, AMELIORATION OR PREVENTION OF INFLUENZA THEREOF | SAVIRA PHARMACEUTICALS GMBH (AT) | 2017-08-10 | — | — | WO | disclosed |