Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPM1B | O75688 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16448666 | 1.00 | PPM1B (0.45) | PPM1BPTPN1PPP1CCCHRM2CHRM4 | |
| SCHEMBL30933030 | 0.95 | PPM1B (0.45) | PPM1BPTPN1PPP1CCCHRM2CHRM4 | |
| SCHEMBL6551846 | 0.90 | PPM1B (0.45) | PPM1BPTPN1PPP1CCCHRM2CHRM4 | |
| SCHEMBL25277941 | 0.87 | PPM1B (0.53) | PPM1BPTPN1PPP1CCCHRM2CHRM4 | |
| SCHEMBL31010896 | 0.87 | PPM1B (0.53) | PPM1BPTPN1PPP1CCCHRM2CHRM4 | |
| SCHEMBL31010895 | 0.87 | PPM1B (0.53) | PPM1BPTPN1PPP1CCCHRM2CHRM4 | |
| SCHEMBL14357849 | 0.84 | CHRM2 (0.42) | PPM1BPTPN1PPP1CCCHRM2CHRM4 | |
| SCHEMBL19250496 | 0.80 | CHRM2 (0.37) | PPM1BPTPN1PPP1CCCHRM2CHRM4 | |
| SCHEMBL15653978 | 0.79 | PPM1B (0.48) | PPM1BPTPN1PPP1CCCYP2C19SMN1; SMN2 | |
| SCHEMBL20306770 | 0.78 | MEN1 (0.47) | PPM1BPTPN1PPP1CCCHRM2CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0352000-A2 | Retroviral protease binding peptides | SMITHKLINE BEECHAM CORPORATION (US) | 1990-01-24 | — | — | EP | disclosed |