SCHEMBL1925104

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1926903	0.90	TP53 (0.42)	PDE4APDE4BPDE4CPDE4DCHRNE
	SCHEMBL1925228	0.89	PDE4A (0.48)	PDE4APDE4BPDE4CPDE4DCHRNE
	SCHEMBL1925767	0.89	PDE4A (0.50)	PDE4APDE4BPDE4CPDE4DMEN1
	SCHEMBL1924288	0.85	PDE4A (0.50)	PDE4APDE4BPDE4CPDE4DMEN1
	Hydrochloric Acid SCHEMBL1925883	0.84	PDE4A (0.49)	PDE4APDE4BPDE4CPDE4DMEN1
	SCHEMBL1925427	0.82	MEN1 (0.38)	PDE4APDE4BPDE4CPDE4DCHRNE
	Hydrochloric Acid SCHEMBL1925483	0.81	MEN1 (0.37)	PDE4APDE4BPDE4CPDE4DCHRNE
	SCHEMBL5584577	0.81	PDE4A (0.48)	PDE4APDE4BPDE4CPDE4DTP53
	SCHEMBL1925431	0.81	PDE4A (0.46)	PDE4APDE4BPDE4CPDE4DMEN1
	SCHEMBL1924763	0.81	GRIN1 (0.42)	PDE4APDE4BPDE4CPDE4DCHRNE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.