Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 17/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22778802 | 0.94 | CNR2 (0.48) | CNR2CNR1 | |
| SCHEMBL25943367 | 0.91 | CNR2 (0.43) | CNR2IDO1 | |
| SCHEMBL27064600 | 0.84 | CNR2 (0.41) | CNR2IDO1 | |
| SCHEMBL22752557 | 0.80 | CNR2 (0.38) | CNR2CNR1 | |
| SCHEMBL23054209 | 0.80 | NOTUM (0.36) | IDO1 | |
| SCHEMBL12459121 | 0.77 | NOTUM (0.40) | — | |
| SCHEMBL25923258 | 0.75 | PDE10A (0.34) | — | |
| SCHEMBL3411519 | 0.74 | ADORA2A (0.43) | — | |
| SCHEMBL25008860 | 0.73 | NPC1 (0.32) | — | |
| SCHEMBL21123750 | 0.72 | TRPV4 (0.42) | CNR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9732083-B2 | Tricyclic gyrase inhibitors | MERCK SHARP & DOHME CORP. (US) | 2017-08-15 | — | — | US | disclosed |