Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 10/20 | 0.53 |
| ▸ | L3MBTL3 | Q96JM7 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.47 |
| ▸ | NOS3 | P29474 | 1/20 | 0.47 |
| ▸ | NOS1 | P29475 | 1/20 | 0.47 |
| ▸ | NOS2 | P35228 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14924459 | 0.88 | HRH3 (0.53) | HRH3L3MBTL3L3MBTL1SMN1; SMN2POLB | |
| SCHEMBL10264415 | 0.86 | L3MBTL3 (0.65) | HRH3L3MBTL3L3MBTL1SMN1; SMN2POLB | |
| SCHEMBL16215683 | 0.85 | HRH3 (0.53) | HRH3L3MBTL3L3MBTL1SMN1; SMN2MBTD1 | |
| SCHEMBL12665893 | 0.85 | HRH3 (0.53) | HRH3L3MBTL3L3MBTL1MBTD1 | |
| SCHEMBL13222431 | 0.84 | L3MBTL3 (0.63) | HRH3L3MBTL3L3MBTL1SMN1; SMN2POLB | |
| SCHEMBL650333 | 0.84 | DRD2 (0.59) | HRH3L3MBTL3L3MBTL1SMN1; SMN2RECQL | |
| SCHEMBL14924012 | 0.84 | HRH3 (0.50) | HRH3L3MBTL3L3MBTL1SMN1; SMN2 | |
| SCHEMBL301839 | 0.84 | HRH3 (0.71) | HRH3SMN1; SMN2POLBNOS3NOS1 | |
| Ammonia Solution, Strong SCHEMBL4962590 | 0.83 | RECQL (0.58) | HRH3SMN1; SMN2RECQL | |
| Hydrochloric Acid SCHEMBL1610029 | 0.83 | RECQL (0.58) | HRH3SMN1; SMN2RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE46511-E1 | Fused pyrimidine derivatives for inhibition of tyrosine kinase activity | HANMI SCIENCE CO., LTD. (KR) | 2017-08-15 | — | — | US | disclosed |