Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 3/20 | 0.31 |
| ▸ | NOS2 | P35228 | 3/20 | 0.31 |
| ▸ | NOS3 | P29474 | 2/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18723476 | 0.74 | SLC6A3 (0.38) | NOS1NOS2NOS3CA1CA2 | |
| SCHEMBL13460948 | 0.74 | — | — | |
| SCHEMBL17826725 | 0.74 | SLC6A3 (0.38) | NOS1NOS2NOS3CA1CA2 | |
| SCHEMBL15038178 | 0.71 | — | — | |
| SCHEMBL17791233 | 0.71 | — | — | |
| SCHEMBL12070404 | 0.71 | — | — | |
| SCHEMBL12070409 | 0.71 | — | — | |
| SCHEMBL25688615 | 0.70 | — | — | |
| SCHEMBL24786154 | 0.67 | GBA1 (0.33) | CA1CA2CA4 | |
| SCHEMBL910154 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3205648-A1 | ESTROGEN RECEPTOR MODULATORS AND USES THEREOF | Seragon Pharmaceuticals, Inc. (US) | 2017-08-16 | — | — | EP | disclosed |