Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | TAS2R38 | P59533 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24624869 | 1.00 | CRBN (0.32) | CRBNEPHX1TAS2R38 | |
| SCHEMBL3753647 | 0.75 | — | — | |
| SCHEMBL3753641 | 0.75 | — | — | |
| SCHEMBL11675748 | 0.74 | ABCC1 (0.33) | — | |
| SCHEMBL6560044 | 0.73 | CRBN (0.35) | CRBNTAS2R38 | |
| SCHEMBL6560042 | 0.73 | CRBN (0.35) | CRBNTAS2R38 | |
| SCHEMBL10170621 | 0.73 | CRBN (0.35) | CRBNTAS2R38 | |
| SCHEMBL21363809 | 0.73 | ANPEP (0.32) | — | |
| SCHEMBL11698336 | 0.71 | CRBN (0.33) | CRBNEPHX1TAS2R38 | |
| Iodide SCHEMBL11701772 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9732083-B2 | Tricyclic gyrase inhibitors | MERCK SHARP & DOHME CORP. (US) | 2017-08-15 | — | — | US | disclosed |