Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | TAS2R38 | P59533 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19251591 | 1.00 | CRBN (0.32) | CRBNEPHX1TAS2R38 | |
| SCHEMBL3753647 | 0.75 | — | — | |
| SCHEMBL3753641 | 0.75 | — | — | |
| SCHEMBL11675748 | 0.74 | ABCC1 (0.33) | — | |
| SCHEMBL6560044 | 0.73 | CRBN (0.35) | CRBNTAS2R38 | |
| SCHEMBL6560042 | 0.73 | CRBN (0.35) | CRBNTAS2R38 | |
| SCHEMBL10170621 | 0.73 | CRBN (0.35) | CRBNTAS2R38 | |
| SCHEMBL21363809 | 0.73 | ANPEP (0.32) | — | |
| SCHEMBL11698336 | 0.71 | CRBN (0.33) | CRBNEPHX1TAS2R38 | |
| Iodide SCHEMBL11701772 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11542262-B2 | Phosphatidylinositol 3-kinase inhibitors | NANJING ZHENGXIANG PHARMACEUTICALS CO., LTD. (CN) | 2023-01-03 | — | — | US | disclosed |
| US-20220220113-A1 | PHOSPHATIDYLINOSITOL 3-KINASE INHIBITORS | NANJING ZHENGXIANG PHARMACEUTICALS CO., LTD. (CN) | 2022-07-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11542262-B2 | Phosphatidylinositol 3-kinase inhibitors | PI4KB, PI4KA, PIK3CD | CRBN 2240/4885EPHX1 3881/4885TAS2R38 4626/4885 |
| US-20220220113-A1 | PHOSPHATIDYLINOSITOL 3-KINASE INHIBITORS | PI4KB, PI4KA, PIK3CD | CRBN 2240/4885EPHX1 3881/4885TAS2R38 4626/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.