Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 8/20 | 0.37 |
| ▸ | PIK3R1 | P27986 | 8/20 | 0.37 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.32 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.32 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29109324 | 1.00 | PIK3CD (0.37) | PIK3CDPIK3R1CACNA1HSLC40A1GRM4 | |
| SCHEMBL30604516 | 1.00 | PIK3CD (0.37) | PIK3CDPIK3R1CACNA1HSLC40A1GRM4 | |
| SCHEMBL30604520 | 1.00 | PIK3CD (0.37) | PIK3CDPIK3R1CACNA1HSLC40A1GRM4 | |
| SCHEMBL30604523 | 0.85 | — | — | |
| SCHEMBL29109291 | 0.85 | — | — | |
| SCHEMBL29109288 | 0.85 | — | — | |
| SCHEMBL29109282 | 0.79 | PIK3CD (0.31) | PIK3CDPIK3R1CACNA1H | |
| SCHEMBL30604511 | 0.79 | PIK3CD (0.31) | PIK3CDPIK3R1CACNA1H | |
| SCHEMBL29109283 | 0.79 | PIK3CD (0.31) | PIK3CDPIK3R1CACNA1H | |
| SCHEMBL19251425 | 0.77 | LMNA (0.36) | PIK3CDPIK3R1SLC40A1GRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117088867-A | Inhalable aromatic ring thiazide and analogue, pharmaceutical composition containing inhalable aromatic ring thiazide and analogue and application of inhalable aromatic ring thiazide and analogue in anti-inflammatory and anti-tumor | 杭州百诚医药科技股份有限公司 | 2023-11-21 | — | — | CN | disclosed |
| WO-2017133655-A1 | BENZOTHIAZINE AND BENZOTHIADIAZINE COMPOUNDS AND PREPARATION AND USE | 浙江大学 | 2017-08-10 | — | — | WO | disclosed |