Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.32 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | THRB | P10828 | 2/20 | 0.32 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.32 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.31 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.31 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.31 |
| ▸ | PIK3R1 | P27986 | 3/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | ELANE | P08246 | 2/20 | 0.30 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19251435 | 0.82 | GRIA2 (0.32) | GRIA2 | |
| SCHEMBL19251617 | 0.77 | PIK3CD (0.37) | GRM4SLC40A1PIK3CDPIK3R1 | |
| SCHEMBL19252679 | 0.75 | LMNA (0.33) | LMNATP53POLBELANE | |
| SCHEMBL19252633 | 0.73 | SLC40A1 (0.37) | LMNATP53GRM4SLC40A1MAPT | |
| SCHEMBL19251605 | 0.71 | LMNA (0.34) | LMNATP53MAPTTHRB | |
| SCHEMBL19252631 | 0.66 | PIK3CD (0.42) | LMNATP53MAPTTHRBPIK3CD | |
| SCHEMBL19251433 | 0.65 | PIK3R1 (0.36) | MAPTPIK3CDPIK3R1 | |
| SCHEMBL19252625 | 0.63 | PIK3R1 (0.43) | SLC40A1THRBPIK3CDPIK3R1 | |
| SCHEMBL18708825 | 0.63 | KDM4E (0.32) | ALDH1A1 | |
| SCHEMBL19251432 | 0.59 | LMNA (0.33) | LMNATP53ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017133655-A1 | BENZOTHIAZINE AND BENZOTHIADIAZINE COMPOUNDS AND PREPARATION AND USE | 浙江大学 | 2017-08-10 | — | — | WO | disclosed |