Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17525226 | 1.00 | ATM (0.33) | ATMALDH1A1MAPTNPSR1 | |
| SCHEMBL3654096 | 1.00 | ATM (0.33) | ATMALDH1A1MAPTNPSR1 | |
| SCHEMBL19277780 | 1.00 | ATM (0.33) | ATMALDH1A1MAPTNPSR1 | |
| SCHEMBL13852669 | 0.69 | — | — | |
| SCHEMBL7738490 | 0.67 | SMN1; SMN2 (0.30) | ATMALDH1A1MAPTNPSR1 | |
| SCHEMBL1104578 | 0.67 | ATM (0.42) | ATMALDH1A1MAPT | |
| SCHEMBL18874109 | 0.67 | ATM (0.42) | ATMALDH1A1MAPT | |
| SCHEMBL406900 | 0.67 | ATM (0.42) | ATMALDH1A1MAPT | |
| SCHEMBL15898403 | 0.67 | ATM (0.33) | ATM | |
| SCHEMBL13852678 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10793581-B2 | Stereochemically defined polypropionates and methods for making and using the same | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2020-10-06 | — | — | US | disclosed |
| US-20200055866-A1 | STEREOCHEMICALLY DEFINED POLYPROPIONATES AND METHODS FOR MAKING AND USING THE SAME | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2020-02-20 | — | — | US | disclosed |
| US-20200055866-A1 | STEREOCHEMICALLY DEFINED POLYPROPIONATES AND METHODS FOR MAKING AND USING THE SAME | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2020-02-20 | — | — | US | disclosed |
| US-10407439-B2 | Stereochemically defined polypropionates and methods for making and using the same | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2019-09-10 | — | — | US | disclosed |
| US-10407439-B2 | Stereochemically defined polypropionates and methods for making and using the same | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2019-09-10 | — | — | US | disclosed |
| US-10160768-B2 | Stereochemically defined polypropionates and methods for making and using the same | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2018-12-25 | — | — | US | disclosed |
| US-20180186810-A1 | STEREOCHEMICALLY DEFINED POLYPROPIONATES AND METHODS FOR MAKING AND USING THE SAME | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2018-07-05 | — | — | US | disclosed |
| US-20180186810-A1 | STEREOCHEMICALLY DEFINED POLYPROPIONATES AND METHODS FOR MAKING AND USING THE SAME | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2018-07-05 | — | — | US | disclosed |
| US-20180186810-A1 | STEREOCHEMICALLY DEFINED POLYPROPIONATES AND METHODS FOR MAKING AND USING THE SAME | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2018-07-05 | — | — | US | disclosed |
| US-20170240560-A1 | STEREOCHEMICALLY DEFINED POLYPROPIONATES AND METHODS FOR MAKING AND USING THE SAME | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2017-08-24 | — | — | US | disclosed |
| US-20170240560-A1 | STEREOCHEMICALLY DEFINED POLYPROPIONATES AND METHODS FOR MAKING AND USING THE SAME | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2017-08-24 | — | — | US | disclosed |
| US-20170240560-A1 | STEREOCHEMICALLY DEFINED POLYPROPIONATES AND METHODS FOR MAKING AND USING THE SAME | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2017-08-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170240560-A1 | STEREOCHEMICALLY DEFINED POLYPROPIONATES AND METHODS FOR MAKING AND USING THE SAME | FDPS, DHPS, ADCYAP1R1 | ATM 4868/4885ALDH1A1 1167/4885MAPT 3175/4885 |
| US-10407439-B2 | Stereochemically defined polypropionates and methods for making and using the same | FDPS, DHPS, ADCYAP1R1 | ATM 4868/4885ALDH1A1 1167/4885MAPT 3175/4885 |
| US-20180186810-A1 | STEREOCHEMICALLY DEFINED POLYPROPIONATES AND METHODS FOR MAKING AND USING THE SAME | FDPS, DHPS, ADCYAP1R1 | ATM 4868/4885ALDH1A1 1167/4885MAPT 3175/4885 |
| US-20200055866-A1 | STEREOCHEMICALLY DEFINED POLYPROPIONATES AND METHODS FOR MAKING AND USING THE SAME | FDPS, DHPS, ADCYAP1R1 | ATM 4868/4885ALDH1A1 1167/4885MAPT 3175/4885 |
| US-10793581-B2 | Stereochemically defined polypropionates and methods for making and using the same | FDPS, DHPS, ADCYAP1R1 | ATM 4868/4885ALDH1A1 1167/4885MAPT 3175/4885 |
| US-10160768-B2 | Stereochemically defined polypropionates and methods for making and using the same | FDPS, DHPS, ADCYAP1R1 | ATM 4868/4885ALDH1A1 1167/4885MAPT 3175/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.