Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 14/20 | 0.39 |
| ▸ | ACACB | O00763 | 2/20 | 0.33 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19252713 | 0.88 | CNR2 (0.36) | CNR2ACACBAOC3 | |
| SCHEMBL12459040 | 0.80 | ACACB (0.44) | CNR2ACACBAOC3 | |
| SCHEMBL21081418 | 0.77 | TAAR1 (0.47) | — | |
| SCHEMBL22778645 | 0.76 | POLB (0.45) | CNR2AOC3 | |
| SCHEMBL21250714 | 0.74 | ADRB1 (0.39) | CNR2ACACB | |
| SCHEMBL12525218 | 0.74 | OGA (0.38) | ACACBAOC3 | |
| SCHEMBL12457553 | 0.71 | ACACB (0.41) | ACACBAOC3 | |
| SCHEMBL18744472 | 0.69 | CNR2 (0.33) | CNR2 | |
| SCHEMBL17057373 | 0.69 | AOC3 (0.35) | ACACBAOC3 | |
| SCHEMBL19252589 | 0.68 | KDM4E (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9732083-B2 | Tricyclic gyrase inhibitors | MERCK SHARP & DOHME CORP. (US) | 2017-08-15 | — | — | US | disclosed |