Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHBG | P04278 | 5/20 | 0.51 |
| ▸ | AKR1B10 | O60218 | 3/20 | 0.51 |
| ▸ | AKR1B1 | P15121 | 3/20 | 0.51 |
| ▸ | GPBAR1 | Q8TDU6 | 3/20 | 0.51 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.51 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.51 |
| ▸ | PGR | P06401 | 1/20 | 0.51 |
| ▸ | SERPINA6 | P08185 | 1/20 | 0.51 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | AR | P10275 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | MGAM | O43451 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.49 |
| ▸ | ATP1A1 | P05023 | 1/20 | 0.48 |
| ▸ | ATP1B1 | P05026 | 1/20 | 0.48 |
| ▸ | ATP1A3 | P13637 | 1/20 | 0.48 |
| ▸ | ATP1B2 | P14415 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10538274 | 1.00 | SHBG (0.51) | SHBGAKR1B10AKR1B1GPBAR1CYP19A1 | |
| SCHEMBL10538271 | 1.00 | SHBG (0.51) | SHBGAKR1B10AKR1B1GPBAR1CYP19A1 | |
| SCHEMBL19253184 | 0.79 | SHBG (0.51) | SHBGAKR1B10AKR1B1GPBAR1CYP19A1 | |
| SCHEMBL19253253 | 0.77 | CYP19A1 (0.50) | SHBGAKR1B10AKR1B1GPBAR1CYP19A1 | |
| SCHEMBL19253227 | 0.76 | AKR1B10 (0.54) | SHBGAKR1B10AKR1B1GPBAR1CYP19A1 | |
| SCHEMBL17543941 | 0.76 | CYP3A4 (0.50) | SHBGAKR1B10AKR1B1GPBAR1SERPINA6 | |
| SCHEMBL10538223 | 0.76 | CYP3A4 (0.50) | SHBGAKR1B10AKR1B1GPBAR1SERPINA6 | |
| SCHEMBL10538227 | 0.76 | CYP3A4 (0.50) | SHBGAKR1B10AKR1B1GPBAR1SERPINA6 | |
| SCHEMBL19253148 | 0.76 | CYP3A4 (0.50) | SHBGAKR1B10AKR1B1GPBAR1SERPINA6 | |
| SCHEMBL19253268 | 0.74 | AKR1B10 (0.47) | SHBGAKR1B10AKR1B1GPBAR1CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3260462-B1 | AMPHIPHILIC COMPOUNDS WITH NEUROPROTECTIVE PROPERTIES | USTAV ORGANICKE CHEMIE A BIOCHEMIE AV CR V V I (CZ) | 2019-04-17 | — | — | EP | disclosed |
| US-10017535-B2 | Amphiphilic compounds with neuroprotective properties | USTAV ORGANICKE CHEMIE A BIOCHEMIE AV CR, V.V.I. (CZ) | 2018-07-10 | — | — | US | disclosed |
| EP-3260462-A1 | AMPHIPHILIC COMPOUNDS WITH NEUROPROTECTIVE PROPERTIES | Ustav Organicke Chemie A Biochemie Av Cr, V.v.i. (CZ) | 2017-12-27 | — | — | EP | disclosed |
| US-20170240588-A1 | AMPHIPHILIC COMPOUNDS WITH NEUROPROTECTIVE PROPERTIES | USTAV ORGANICKE CHEMIE A BIOCHEMIE AV CR, V.V.I. (CZ) | 2017-08-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170240588-A1 | AMPHIPHILIC COMPOUNDS WITH NEUROPROTECTIVE PROPERTIES | GAP43, GRIN2A, GRIN3A | SHBG 3674/4885AKR1B10 3701/4885AKR1B1 3535/4885 |
| US-10017535-B2 | Amphiphilic compounds with neuroprotective properties | GAP43, GRIN2A, GRIN3A | SHBG 3674/4885AKR1B10 3701/4885AKR1B1 3535/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.