Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 5/20 | 0.71 |
| ▸ | GRIN2B | Q13224 | 5/20 | 0.71 |
| ▸ | VDR | P11473 | 3/20 | 0.64 |
| ▸ | ABCC4 | O15439 | 3/20 | 0.64 |
| ▸ | ST6GAL1 | P15907 | 2/20 | 0.63 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.58 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.57 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.55 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.55 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.55 |
| ▸ | POLA1 | P09884 | 1/20 | 0.54 |
| ▸ | CDC25A | P30304 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19733274 | 0.91 | GRIN1 (0.84) | GRIN1GRIN2BVDRABCC4ST6GAL1 | |
| SCHEMBL19253196 | 0.90 | GRIN1 (0.82) | GRIN1GRIN2BVDRABCC4ST6GAL1 | |
| SCHEMBL19253282 | 0.85 | GRIN1 (0.64) | GRIN1GRIN2BVDRABCC4ST6GAL1 | |
| SCHEMBL19253281 | 0.85 | GRIN1 (0.64) | GRIN1GRIN2BVDRABCC4ST6GAL1 | |
| SCHEMBL19253158 | 0.81 | GRIN1 (0.83) | GRIN1GRIN2BVDRABCC4GRIN2D | |
| SCHEMBL19253197 | 0.81 | GRIN1 (1.00) | GRIN1GRIN2BVDRABCC4ABCC1 | |
| SCHEMBL13347854 | 0.80 | VDR (0.76) | GRIN1GRIN2BVDRABCC4ST6GAL1 | |
| SCHEMBL13311422 | 0.80 | VDR (0.76) | GRIN1GRIN2BVDRABCC4ST6GAL1 | |
| SCHEMBL17124639 | 0.80 | VDR (0.76) | GRIN1GRIN2BVDRABCC4ST6GAL1 | |
| SCHEMBL19253208 | 0.80 | GRIN1 (0.81) | GRIN1GRIN2BST6GAL1GRIN2DGRIN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3186267-B1 | AMPHIPHILIC COMPOUNDS WITH NEUROPROTECTIVE PROPERTIES | USTAV ORGANICKE CHEMIE A BIOCHEMIE AV CR V V I (CZ) | 2019-10-02 | — | — | EP | claimed |
| US-10017535-B2 | Amphiphilic compounds with neuroprotective properties | USTAV ORGANICKE CHEMIE A BIOCHEMIE AV CR, V.V.I. (CZ) | 2018-07-10 | — | — | US | claimed |
| EP-3186267-B1 | AMPHIPHILIC COMPOUNDS WITH NEUROPROTECTIVE PROPERTIES | USTAV ORGANICKE CHEMIE A BIOCHEMIE AV CR V V I (CZ) | 2019-10-02 | — | — | EP | disclosed |
| US-10017535-B2 | Amphiphilic compounds with neuroprotective properties | USTAV ORGANICKE CHEMIE A BIOCHEMIE AV CR, V.V.I. (CZ) | 2018-07-10 | — | — | US | disclosed |
| EP-3260462-A1 | AMPHIPHILIC COMPOUNDS WITH NEUROPROTECTIVE PROPERTIES | Ustav Organicke Chemie A Biochemie Av Cr, V.v.i. (CZ) | 2017-12-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10017535-B2 | Amphiphilic compounds with neuroprotective properties | GAP43, GRIN2A, GRIN3A | GRIN1 14/4885GRIN2B 8/4885VDR 1210/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.