Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.57 |
| ▸ | NFE2L2 | Q16236 | 7/20 | 0.48 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.42 |
| ▸ | CYP21A2 | P08686 | 1/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | KDM4A | O75164 | 2/20 | 0.41 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17011126 | 1.00 | APP (0.57) | APPNFE2L2CYP17A1CYP21A2CYP11B1 | |
| SCHEMBL4268029 | 0.89 | ALDH1A1 (0.48) | APPCYP17A1CYP21A2CYP11B1ALDH1A1 | |
| SCHEMBL12991150 | 0.89 | ALDH1A1 (0.48) | APPCYP17A1CYP21A2CYP11B1ALDH1A1 | |
| SCHEMBL4268024 | 0.89 | ALDH1A1 (0.48) | APPCYP17A1CYP21A2CYP11B1ALDH1A1 | |
| SCHEMBL17248030 | 0.89 | ALDH1A1 (0.48) | APPCYP17A1CYP21A2CYP11B1ALDH1A1 | |
| SCHEMBL13636755 | 0.89 | APP (0.68) | APPNFE2L2PTGS1KDM4AKDM2A | |
| SCHEMBL4585021 | 0.89 | ALDH1A1 (0.48) | APPCYP17A1CYP21A2CYP11B1ALDH1A1 | |
| SCHEMBL18381153 | 0.87 | SMN1; SMN2 (0.43) | APPALDH1A1KDM4ERAB9AMAPT | |
| SCHEMBL12215526 | 0.87 | SMN1; SMN2 (0.43) | APPALDH1A1KDM4ERAB9AMAPT | |
| SCHEMBL13992019 | 0.83 | APP (0.61) | APPNFE2L2CYP17A1CYP21A2CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170244034-A1 | AROMATIC COMPOUND AND ORGANIC LIGHT-EMITTING DIODE INCLUDING THE SAME | NATIONAL TSING HUA UNIVERSITY (TW) | 2017-08-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170244034-A1 | AROMATIC COMPOUND AND ORGANIC LIGHT-EMITTING DIODE INCLUDING THE SAME | ARNT, AHR, CYP1A1 | APP 794/4885NFE2L2 51/4885CYP17A1 339/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.