SCHEMBL19253346

SCHEMBL19253346

O=C(O)c1cc2cc3c4cc5ccccc5cc4c4cc5ccccc5cc4c3cc2c(C(=O)O)c1C(=O)O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 1/20 0.50
MEN1 O00255 3/20 0.49
KMT2A Q03164 3/20 0.49
RXFP1 Q9HBX9 1/20 0.49
KDM4E B2RXH2 3/20 0.48
ALDH1A1 P00352 2/20 0.48
HPGD P15428 2/20 0.48
CYP1A2 P05177 2/20 0.48
CYP2C19 P33261 2/20 0.48
HSD17B10 Q99714 2/20 0.48
GLA P06280 1/20 0.48
TP53 P04637 1/20 0.45
HIF1A Q16665 1/20 0.45
MAPT P10636 2/20 0.45
GFER P55789 1/20 0.45
NGLY1 Q96IV0 1/20 0.45
NR4A1 P22736 1/20 0.44
NR4A2 P43354 1/20 0.44
NR4A3 Q92570 1/20 0.44
PTPN1 P18031 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL471867 0.95 KDM4E (0.55) IDO1MEN1KMT2ARXFP1KDM4E
SCHEMBL1373667 0.85 KDM4E (0.36) IDO1MEN1KMT2ARXFP1KDM4E
SCHEMBL7058415 0.83 KDM4E (0.47) IDO1MEN1KMT2ARXFP1KDM4E
SCHEMBL28652 0.83 MEN1 (0.70) IDO1MEN1KMT2ARXFP1KDM4E
SCHEMBL31401681 0.83 MEN1 (0.70) IDO1MEN1KMT2ARXFP1KDM4E
SCHEMBL30354048 0.83 MEN1 (0.70) IDO1MEN1KMT2ARXFP1KDM4E
SCHEMBL10417205 0.81 MEN1 (0.68) IDO1MEN1KMT2ARXFP1KDM4E
Potassium SCHEMBL31214964 0.81 MEN1 (0.68) IDO1MEN1KMT2ARXFP1KDM4E
SCHEMBL31214852 0.81 MEN1 (0.68) IDO1MEN1KMT2ARXFP1KDM4E
Ammonia Solution, Strong SCHEMBL31214891 0.81 MEN1 (0.68) IDO1MEN1KMT2ARXFP1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250026889-A1 TWO DIMENSIONAL POLYMERS COMPRISED OF A COMBINATION OF STIFF AND COMPLIANT MOLECULAR UNITS U.S. GOVERNMENT, AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) 2025-01-23 US disclosed
US-12110367-B2 Two-dimensional polymers comprised of a combination of stiff and compliant molecular units THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) 2024-10-08 US disclosed
US-20200148827-A1 TWO-DIMENSIONAL POLYMERS COMPRISED OF A COMBINATION OF STIFF AND COMPLIANT MOLECULAR UNITS THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY 2020-05-14 US disclosed
US-10590241-B2 Two-dimensional polymers comprised of a combination of stiff and compliant molecular units THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) 2020-03-17 US disclosed
US-20170240706-A1 TWO-DIMENSIONAL POLYMERS COMPRISED OF A COMBINATION OF STIFF AND COMPLIANT MOLECULAR UNITS ARMY, UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE 2017-08-24 US disclosed