SCHEMBL7058415

SCHEMBL7058415

O=C(O)c1cc2cc3ccccc3cc2c(C(=O)OC(=O)c2c(C(=O)O)c(C(=O)O)cc3cc4ccccc4cc23)c1C(=O)O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.47
ALDH1A1 P00352 4/20 0.47
HPGD P15428 3/20 0.47
HSD17B10 Q99714 3/20 0.47
CYP1A2 P05177 2/20 0.47
CYP2C19 P33261 2/20 0.47
MEN1 O00255 2/20 0.47
KMT2A Q03164 2/20 0.47
GLA P06280 1/20 0.47
IDO1 P14902 1/20 0.45
MAPT P10636 1/20 0.41
GFER P55789 1/20 0.41
NGLY1 Q96IV0 1/20 0.41
CDC25B P30305 3/20 0.40
PTPN1 P18031 1/20 0.40
NR4A1 P22736 1/20 0.40
NR4A2 P43354 1/20 0.40
NR4A3 Q92570 1/20 0.40
GAA P10253 1/20 0.39
ME2 P23368 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL471867 0.89 KDM4E (0.55) KDM4EALDH1A1HPGDHSD17B10CYP1A2
SCHEMBL29628947 0.88 KDM4E (0.50) KDM4EALDH1A1HPGDHSD17B10CYP1A2
SCHEMBL6432594 0.87 ALDH1A1 (0.59) KDM4EALDH1A1HPGDHSD17B10CYP1A2
SCHEMBL19253346 0.83 IDO1 (0.50) KDM4EALDH1A1HPGDHSD17B10CYP1A2
SCHEMBL1270917 0.83 MEN1 (0.49) KDM4EALDH1A1HPGDHSD17B10CYP1A2
SCHEMBL30401444 0.80 KDM4E (0.48) KDM4EALDH1A1HPGDHSD17B10CYP1A2
SCHEMBL3448030 0.80 KDM4E (0.42) KDM4EALDH1A1HPGDHSD17B10CYP1A2
SCHEMBL26963240 0.78 IDO1 (0.56) KDM4EALDH1A1HPGDHSD17B10CYP1A2
SCHEMBL3446987 0.77 KDM4E (0.41) KDM4EALDH1A1HPGDHSD17B10CYP1A2
SCHEMBL31125071 0.77 KDM4E (0.69) KDM4EALDH1A1HPGDHSD17B10CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1046674-B1 Polyester resin composition MITSUBISHI GAS CHEMICAL CO (JP) 2004-07-21 EP disclosed
US-6319575-B1 MELT KNEADING A POLYESTER RESIN MIXTURE WITH POLYAMIDES MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2001-11-20 US disclosed
EP-1046674-A2 Polyester resin composition MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2000-10-25 EP disclosed