SCHEMBL1925341

SCHEMBL1925341

c1ccc2c3cnc[nH]c-3nc2c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.41
IDO1 P14902 2/20 0.41
HPGD P15428 5/20 0.40
LMNA P02545 2/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
TNKS O95271 1/20 0.40
PARP1 P09874 1/20 0.40
TNKS2 Q9H2K2 1/20 0.40
ADRA2A P08913 6/20 0.39
ADRA2B P18089 6/20 0.39
ADRA2C P18825 6/20 0.39
ADRA1A P35348 6/20 0.39
ADRA1D P25100 5/20 0.39
ADRA1B P35368 5/20 0.39
ALDH1A1 P00352 3/20 0.39
HSD17B10 Q99714 2/20 0.39
MAPT P10636 2/20 0.39
KDM4E B2RXH2 2/20 0.39
ALOX15 P16050 1/20 0.39
APOBEC3G Q9HC16 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19066458 0.75 CSNK2A2 (0.44) KDM4E
SCHEMBL1180188 0.73 NPC1 (0.47) CYP3A4IDO1HPGDLMNASMN1; SMN2
SCHEMBL2391062 0.70 CYP3A4 (0.41) CYP3A4IDO1ADRA2AADRA2BADRA2C
SCHEMBL7738496 0.69 HPGD (0.39) CYP3A4HPGDLMNASMN1; SMN2TNKS
SCHEMBL18148991 0.67 CYP11B1 (0.50) CYP3A4IDO1ADRA2AADRA2BADRA2C
SCHEMBL4506826 0.66 MAPK10 (0.54) CYP3A4IDO1ADRA2AADRA2BADRA2C
SCHEMBL4512339 0.66 KDM4E (0.42) CYP3A4IDO1HPGDADRA2AADRA2B
SCHEMBL4509516 0.66 RAD52 (0.48) CYP3A4IDO1HPGDLMNASMN1; SMN2
SCHEMBL4504196 0.66 CDK4 (0.41) CYP3A4IDO1HPGDLMNASMN1; SMN2
SCHEMBL24067296 0.66 KDR (0.59) HPGDLMNASMN1; SMN2ALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 258 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260028588-A1 DIFFERENTIATION OF STEM CELLS IN SUSPENSION CULTURE UMOJA BIOPHARMA, INC. (US) 2026-01-29 US claimed
US-20250367290-A1 ENGINEERED STEM CELLS AND USES THEREOF Umoja Bioharma, Inc. (US) 2025-12-04 US claimed
US-20250354118-A1 COMPOSITIONS AND METHODS FOR NK CELL DIFFERENTIATION UMOJA BIOPHARMA, INC. (US) 2025-11-20 US claimed
EP-4562133-A1 DIFFERENTIATION OF STEM CELLS IN SUSPENSION CULTURE Umoja Biopharma, Inc. (US) 2025-06-04 EP claimed
EP-4536693-A1 ENGINEERED STEM CELLS AND USES THEREOF Umoja Biopharma, Inc. (US) 2025-04-16 EP claimed
EP-4536811-A2 COMPOSITIONS AND METHODS FOR NK CELL DIFFERENTIATION Umoja Biopharma, Inc. (US) 2025-04-16 EP claimed
EP-4381048-A1 METHODS OF T CELL PRODUCTION Adaptimmune Limited (GB) 2024-06-12 EP claimed
WO-2024026391-A1 DIFFERENTIATION OF STEM CELLS IN SUSPENSION CULTURE UMOJA BIOPHARMA, INC. (US) 2024-02-01 WO claimed
WO-2023240282-A1 ENGINEERED STEM CELLS AND USES THEREOF UMOJA BIOPHARMA, INC. (US) 2023-12-14 WO claimed
WO-2023240248-A2 COMPOSITIONS AND METHODS FOR NK CELL DIFFERENTIATION UMOJA BIOPHARMA, INC. (US) 2023-12-14 WO claimed
WO-2017066530-A1 NATURAL KILLER CELLS AND ILC3 CELLS AND USES THEREOF ANTHROGENSIS CORPORATION (US) 2017-04-20 WO claimed
WO-2016191879-A1 METHODS FOR CULTURING AND/OR DIFFERENTIATING HEMATOPOIETIC STEM CELLS INTO PROGENITORS AND USES THEREOF Héma-Québec (CA) 2016-12-08 WO claimed
WO-2016109661-A1 NATURAL KILLER CELLS AND USES THEREOF ANTHROGENESIS CORPORATION (US) 2016-07-07 WO claimed
EP-1442039-A1 PYRIMIDO (4,5-B) INDOLE DERIVATIVES Bayer HealthCare AG (DE) 2004-08-04 EP claimed
WO-2003037898-A1 PYRIMIDO [4,5-B] INDOLE DERIVATIVES BAYER HEALTHCARE AG (DE) 2003-05-08 WO claimed
EP-0964865-B1 PHARMACEUTICALLY ACTIVE TRICYCLIC AMINES UPJOHN CO (US) 2003-03-05 EP claimed
EP-0964865-A2 PHARMACEUTICALLY ACTIVE TRICYCLIC AMINES PHARMACIA & UPJOHN COMPANY (US) 1999-12-22 EP claimed
WO-1998042708-A2 PHARMACEUTICALLY ACTIVE TRICYCLIC AMINES PHARMACIA & UPJOHN COMPANY (US) 1998-10-01 WO claimed
EP-0812322-A1 PYRIMIDO 4,5-b]INDOLES PHARMACIA & UPJOHN COMPANY (US) 1997-12-17 EP claimed
WO-1996026941-A1 PYRIMIDO[4,5-b]INDOLES PHARMACIA & UPJOHN COMPANY (US) 1996-09-06 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250367290-A1 ENGINEERED STEM CELLS AND USES THEREOF IL2RA, IL2, IL15RA CYP3A4 4425/4885IDO1 2248/4885HPGD 1948/4885
US-20260028588-A1 DIFFERENTIATION OF STEM CELLS IN SUSPENSION CULTURE BMP4, FLT4, FGF2 CYP3A4 2987/4885IDO1 1537/4885HPGD 2909/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.