SCHEMBL24067296

SCHEMBL24067296

c1ccc2c(-c3nc4ccccc4[nH]3)cncc2c1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDR P35968 3/20 0.59
ERBB2 P04626 1/20 0.59
CDK1 P06493 1/20 0.59
ALDH1A1 P00352 11/20 0.56
NPC1 O15118 10/20 0.56
KDM4E B2RXH2 10/20 0.56
RAB9A P51151 9/20 0.56
HPGD P15428 8/20 0.56
HSD17B10 Q99714 7/20 0.56
MAPK1 P28482 1/20 0.56
SMN1; SMN2 Q16637 6/20 0.56
NPSR1 Q6W5P4 4/20 0.56
PKM P14618 3/20 0.56
TP53 P04637 2/20 0.56
ABCB11 O95342 1/20 0.56
MAPT P10636 3/20 0.53
HTT P42858 2/20 0.53
GAA P10253 2/20 0.53
L3MBTL1 Q9Y468 1/20 0.53
GPR55 Q9Y2T6 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL784353 0.81 NPC1 (0.66) KDRCDK1ALDH1A1NPC1KDM4E
SCHEMBL31677102 0.81 NPC1 (0.66) KDRCDK1ALDH1A1NPC1KDM4E
SCHEMBL29825055 0.81 NPC1 (0.66) KDRCDK1ALDH1A1NPC1KDM4E
Benzene SCHEMBL29179821 0.80 RAB9A (0.64) KDRCDK1ALDH1A1NPC1KDM4E
SCHEMBL28116783 0.79 NPC1 (0.72) KDRCDK1ALDH1A1NPC1KDM4E
SCHEMBL5513117 0.78 MAP3K8 (0.63) KDRERBB2CDK1FGFR1FLT1
SCHEMBL21297858 0.77 HPGD (0.63) KDRCDK1ALDH1A1NPC1KDM4E
SCHEMBL227743 0.77 NPC1 (0.78) KDRCDK1ALDH1A1NPC1KDM4E
SCHEMBL20677815 0.75 NPC1 (0.75) KDRCDK1ALDH1A1NPC1KDM4E
SCHEMBL27824963 0.74 RAB9A (0.60) KDRCDK1ALDH1A1NPC1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210371992-A1 ELECTROCHEMICAL ORGANIC REACTION SETUP AND METHODS PIRAMAL PHARMA LIMITED (IN) 2021-12-02 US disclosed