SCHEMBL19253886

SCHEMBL19253886

Brc1c2ccccc2c(-c2cccc(-c3ccccc3)n2)c2ccccc12

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.59
KMT2A Q03164 2/20 0.59
RAB9A P51151 1/20 0.59
ASIC3 Q9UHC3 1/20 0.46
MAPT P10636 2/20 0.43
L3MBTL1 Q9Y468 2/20 0.43
KDM4E B2RXH2 2/20 0.43
MAPK1 P28482 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
HPGD P15428 3/20 0.39
ALDH1A1 P00352 2/20 0.39
POLB P06746 1/20 0.39
HSD17B10 Q99714 1/20 0.39
ACHE P22303 1/20 0.37
CCR4 P51679 1/20 0.36
CYP1A2 P05177 1/20 0.36
CYP3A4 P08684 1/20 0.36
CYP2C9 P11712 1/20 0.36
CYP2C19 P33261 1/20 0.36
ADORA2A P29274 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12345158 0.90 MEN1 (0.73) MEN1KMT2ARAB9AASIC3MAPT
SCHEMBL18718020 0.88 RAB9A (0.44) MEN1KMT2ARAB9AASIC3MAPT
SCHEMBL12435997 0.86 MEN1 (0.67) MEN1KMT2ARAB9AASIC3MAPT
SCHEMBL30450198 0.84 PARP1 (0.42) MEN1KMT2ARAB9AASIC3MAPT
SCHEMBL21518524 0.84 PARP1 (0.42) MEN1KMT2ARAB9AASIC3MAPT
SCHEMBL12436890 0.83 MEN1 (0.61) MEN1KMT2ARAB9AASIC3MAPT
SCHEMBL971029 0.79 MEN1 (0.51) MEN1KMT2AMAPTL3MBTL1KDM4E
SCHEMBL21445685 0.78 MEN1 (0.47) MEN1KMT2AMAPTL3MBTL1KDM4E
SCHEMBL12259731 0.77 CYP19A1 (0.57) MEN1KMT2ARAB9AKDM4EHPGD
SCHEMBL58442 0.77 MEN1 (1.00) MEN1KMT2ARAB9AASIC3MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107104204-B Organic light emitting device 三星显示有限公司 2021-03-05 CN disclosed
EP-3214153-B1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO LTD (KR) 2020-03-25 EP disclosed
US-10096780-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2018-10-09 US disclosed
EP-3214153-A1 ORGANIC LIGHT-EMITTING DEVICE Samsung Display Co., Ltd. (KR) 2017-09-06 EP disclosed
US-20170244048-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2017-08-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170244048-A1 ORGANIC LIGHT-EMITTING DEVICE CYBA, SLC1A2, L1CAM MEN1 2263/4885KMT2A 2950/4885RAB9A 2734/4885
US-10096780-B2 Organic light-emitting device CYBA, SLC1A2, L1CAM MEN1 2263/4885KMT2A 2950/4885RAB9A 2734/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.