Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3R1 | P27986 | 17/20 | 0.58 |
| ▸ | PIK3CD | O00329 | 16/20 | 0.58 |
| ▸ | PIK3CB | P42338 | 4/20 | 0.58 |
| ▸ | PIK3CG | P48736 | 4/20 | 0.58 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | PNMT | P11086 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19254024 | 1.00 | PIK3R1 (0.58) | PIK3R1PIK3CDPIK3CBPIK3CGPIK3CA | |
| SCHEMBL19254025 | 1.00 | PIK3R1 (0.58) | PIK3R1PIK3CDPIK3CBPIK3CGPIK3CA | |
| SCHEMBL19252635 | 0.77 | PIK3R1 (0.48) | PIK3R1PIK3CDPIK3CBPIK3CGPIK3CA | |
| SCHEMBL19252980 | 0.76 | PIK3CD (0.81) | PIK3R1PIK3CDPIK3CBPIK3CGPIK3CA | |
| SCHEMBL19251387 | 0.75 | PIK3R1 (0.77) | PIK3R1PIK3CDPIK3CBPIK3CGPIK3CA | |
| SCHEMBL19252638 | 0.75 | PIK3R1 (0.46) | PIK3R1PIK3CDPIK3CBPIK3CGPIK3CA | |
| SCHEMBL19251607 | 0.75 | PIK3CD (1.00) | PIK3R1PIK3CDPIK3CBPIK3CGPIK3CA | |
| SCHEMBL19252626 | 0.75 | PIK3CD (1.00) | PIK3R1PIK3CDPIK3CBPIK3CGPIK3CA | |
| SCHEMBL29109339 | 0.74 | PIK3R1 (0.39) | PIK3R1PIK3CDPIK3CBPIK3CGPIK3CA | |
| SCHEMBL29109342 | 0.74 | PIK3R1 (0.39) | PIK3R1PIK3CDPIK3CBPIK3CGPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017133655-A1 | BENZOTHIAZINE AND BENZOTHIADIAZINE COMPOUNDS AND PREPARATION AND USE | 浙江大学 | 2017-08-10 | — | — | WO | disclosed |