Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3R1 | P27986 | 12/20 | 0.46 |
| ▸ | PIK3CD | O00329 | 11/20 | 0.46 |
| ▸ | PIK3CB | P42338 | 4/20 | 0.44 |
| ▸ | PIK3CG | P48736 | 4/20 | 0.44 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19252635 | 0.90 | PIK3R1 (0.48) | PIK3R1PIK3CDPIK3CBPIK3CGPIK3CA | |
| SCHEMBL19254024 | 0.75 | PIK3R1 (0.58) | PIK3R1PIK3CDPIK3CBPIK3CGPIK3CA | |
| SCHEMBL19252631 | 0.69 | PIK3CD (0.42) | PIK3R1PIK3CDALDH1A1LMNAMAPT | |
| SCHEMBL19251433 | 0.68 | PIK3R1 (0.36) | PIK3R1PIK3CDPIK3CBPIK3CGPIK3CA | |
| SCHEMBL29109339 | 0.62 | PIK3R1 (0.39) | PIK3R1PIK3CDPIK3CBPIK3CGPIK3CA | |
| SCHEMBL29109342 | 0.62 | PIK3R1 (0.39) | PIK3R1PIK3CDPIK3CBPIK3CGPIK3CA | |
| SCHEMBL28450556 | 0.59 | CACNA1G (0.40) | ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL21277645 | 0.59 | RORC (0.33) | — | |
| SCHEMBL10919354 | 0.58 | SIGMAR1 (0.43) | ALDH1A1LMNAMEN1HPGDKMT2A | |
| SCHEMBL19251432 | 0.57 | LMNA (0.33) | ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017133655-A1 | BENZOTHIAZINE AND BENZOTHIADIAZINE COMPOUNDS AND PREPARATION AND USE | 浙江大学 | 2017-08-10 | — | — | WO | disclosed |