Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT6 | Q96LA8 | 2/20 | 0.37 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.37 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.37 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.37 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 7/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.30 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19309064 | 0.85 | MEN1 (0.35) | MEN1KMT2AFAAHMAPK1TSHR | |
| SCHEMBL18596786 | 0.82 | MEN1 (0.37) | MEN1KMT2AFAAHMAPK1TSHR | |
| SCHEMBL23475900 | 0.82 | MEN1 (0.43) | MEN1KMT2AFAAHMAPK1TSHR | |
| SCHEMBL19000007 | 0.81 | MEN1 (0.37) | MEN1KMT2AFAAHMAPK1TSHR | |
| SCHEMBL18458618 | 0.81 | MEN1 (0.46) | MEN1KMT2AFAAHMAPK1TSHR | |
| SCHEMBL7721231 | 0.81 | CA12 (0.39) | MEN1KMT2AFAAHMAPK1TSHR | |
| SCHEMBL12038684 | 0.80 | PRMT1 (0.42) | PRMT6PRMT3CARM1PRMT1PRMT8 | |
| SCHEMBL19880173 | 0.78 | MEN1 (0.35) | MEN1KMT2AFAAHMAPK1TSHR | |
| SCHEMBL13997592 | 0.77 | PRMT3 (0.39) | PRMT6PRMT3CARM1PRMT1PRMT8 | |
| SCHEMBL29955601 | 0.76 | TSHR (0.35) | MEN1KMT2AFAAHMAPK1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9730955-B2 | Polymer-conjugated MetAP2 inhibitors, and therapeutic methods of use thereof | SYNDEVRX, INC. (US) | 2017-08-15 | — | — | US | disclosed |