Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 7/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | CTSK | P43235 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29952827 | 0.81 | TSHR (0.38) | TSHRMEN1KMT2AFAAHMAPK1 | |
| SCHEMBL23475900 | 0.80 | MEN1 (0.43) | TSHRMEN1KMT2AFAAHMAPK1 | |
| SCHEMBL19000007 | 0.79 | MEN1 (0.37) | TSHRMEN1KMT2AFAAHMAPK1 | |
| SCHEMBL7721231 | 0.79 | CA12 (0.39) | TSHRMEN1KMT2AFAAHMAPK1 | |
| SCHEMBL18458618 | 0.79 | MEN1 (0.46) | TSHRMEN1KMT2AFAAHMAPK1 | |
| SCHEMBL29953331 | 0.79 | ALDH1A1 (0.33) | ALDH1A1HPGDLMNA | |
| SCHEMBL29951451 | 0.79 | ALDH1A1 (0.42) | TSHRMEN1KMT2AFAAHMAPK1 | |
| SCHEMBL18596786 | 0.77 | MEN1 (0.37) | TSHRMEN1KMT2AFAAHMAPK1 | |
| SCHEMBL19309064 | 0.76 | MEN1 (0.35) | TSHRMEN1KMT2AFAAHMAPK1 | |
| SCHEMBL19254211 | 0.76 | PRMT6 (0.37) | TSHRMEN1KMT2AFAAHMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |