Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.71 |
| ▸ | NAAA | Q02083 | 2/20 | 0.69 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.68 |
| ▸ | NPC1 | O15118 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 1/20 | 0.61 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.59 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.59 |
| ▸ | TP53 | P04637 | 3/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.55 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.54 |
| ▸ | MLYCD | O95822 | 1/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19254326 | 1.00 | SMN1; SMN2 (0.71) | SMN1; SMN2NAAAL3MBTL1NPC1RAB9A | |
| SCHEMBL13763462 | 1.00 | SMN1; SMN2 (0.71) | SMN1; SMN2NAAAL3MBTL1NPC1RAB9A | |
| SCHEMBL19124111 | 1.00 | SMN1; SMN2 (0.71) | SMN1; SMN2NAAAL3MBTL1NPC1RAB9A | |
| SCHEMBL10085277 | 0.98 | SMN1; SMN2 (0.73) | SMN1; SMN2NAAAL3MBTL1NPC1RAB9A | |
| SCHEMBL842634 | 0.94 | SMN1; SMN2 (0.81) | SMN1; SMN2NAAAL3MBTL1NPC1RAB9A | |
| SCHEMBL9492626 | 0.94 | NPC1 (0.68) | SMN1; SMN2NAAAL3MBTL1NPC1RAB9A | |
| SCHEMBL6535127 | 0.91 | SMN1; SMN2 (0.87) | SMN1; SMN2NAAAL3MBTL1MAPTLMNA | |
| SCHEMBL131829 | 0.91 | SMN1; SMN2 (0.87) | SMN1; SMN2NAAAL3MBTL1MAPTLMNA | |
| SCHEMBL1753828 | 0.87 | L3MBTL1 (0.71) | SMN1; SMN2L3MBTL1NPC1RAB9AMAPT | |
| SCHEMBL24011629 | 0.87 | HDAC3 (0.61) | SMN1; SMN2NAAAL3MBTL1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017136689-A1 | PURINE COMPOUNDS POSSESSING ANTICANCER ACTIVITY | ACADEMIA SINICA (TW) | 2017-08-10 | — | — | WO | disclosed |