SCHEMBL6535127

SCHEMBL6535127

CCCCCCNC(=O)c1cccc(C(=O)NCCCCCC)c1

nearest known ligand 0.87

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.87
NAAA Q02083 4/20 0.78
L3MBTL1 Q9Y468 2/20 0.66
LMNA P02545 1/20 0.60
MLYCD O95822 1/20 0.59
GAA P10253 1/20 0.58
MAPT P10636 1/20 0.58
CA2 P00918 1/20 0.57
ALDH1A1 P00352 1/20 0.55
POLB P06746 1/20 0.55
TP53BP1 Q12888 1/20 0.55
THRA P10827 1/20 0.55
THRB P10828 1/20 0.55
TSHR P16473 1/20 0.54
HTT P42858 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL131829 1.00 SMN1; SMN2 (0.87) SMN1; SMN2NAAAL3MBTL1LMNAMLYCD
SCHEMBL13599780 0.94 SMN1; SMN2 (0.77) SMN1; SMN2NAAAL3MBTL1LMNAMLYCD
SCHEMBL16117373 0.93 SMN1; SMN2 (1.00) SMN1; SMN2NAAAL3MBTL1LMNAGAA
SCHEMBL6535319 0.92 SMN1; SMN2 (0.74) SMN1; SMN2NAAAL3MBTL1LMNAMLYCD
SCHEMBL10174301 0.92 SMN1; SMN2 (0.79) SMN1; SMN2NAAAL3MBTL1LMNAMLYCD
SCHEMBL13328782 0.92 SMN1; SMN2 (0.79) SMN1; SMN2NAAAL3MBTL1LMNAMLYCD
SCHEMBL11234806 0.91 SMN1; SMN2 (0.71) SMN1; SMN2NAAAL3MBTL1LMNAMLYCD
SCHEMBL19254326 0.91 SMN1; SMN2 (0.71) SMN1; SMN2NAAAL3MBTL1LMNAMLYCD
SCHEMBL19254325 0.91 SMN1; SMN2 (0.71) SMN1; SMN2NAAAL3MBTL1LMNAMLYCD
SCHEMBL5370898 0.91 SMN1; SMN2 (0.77) SMN1; SMN2NAAAL3MBTL1LMNAMLYCD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1099137-A4 DISPERSION AIDS FOR OPTICAL BRIGHTENERS IN POLYOLEFINS EASTMAN CHEM CO (US) 2004-10-06 EP claimed
US-6312822-B1 AS POLAR ADDITIVES POLYMERIC ESTERS, OLIGOMERIC ESTERS, POLYAMIDES, FATTY ACIDS AMIDES OF ALIPHATIC AMINES AND DIAMINES, COPOLYMERS OF POLY(ETHYLENE-COACRYLIC ACID), OR ESTERS OF POLY(ALKYLENE GLYCOLS) EASTMAN CHEM CO (US) 2001-11-06 US claimed
EP-1099137-A1 DISPERSION AIDS FOR OPTICAL BRIGHTENERS IN POLYOLEFINS EASTMAN CHEMICAL COMPANY (US) 2001-05-16 EP claimed
WO-1999061955-A1 DISPERSION AIDS FOR OPTICAL BRIGHTENERS IN POLYOLEFINS EASTMAN CHEMICAL COMPANY (US) 1999-12-02 WO claimed
EP-1099137-A4 DISPERSION AIDS FOR OPTICAL BRIGHTENERS IN POLYOLEFINS EASTMAN CHEM CO (US) 2004-10-06 EP disclosed
US-6312822-B1 AS POLAR ADDITIVES POLYMERIC ESTERS, OLIGOMERIC ESTERS, POLYAMIDES, FATTY ACIDS AMIDES OF ALIPHATIC AMINES AND DIAMINES, COPOLYMERS OF POLY(ETHYLENE-COACRYLIC ACID), OR ESTERS OF POLY(ALKYLENE GLYCOLS) EASTMAN CHEM CO (US) 2001-11-06 US disclosed
EP-1099137-A1 DISPERSION AIDS FOR OPTICAL BRIGHTENERS IN POLYOLEFINS EASTMAN CHEMICAL COMPANY (US) 2001-05-16 EP disclosed
WO-1999061955-A1 DISPERSION AIDS FOR OPTICAL BRIGHTENERS IN POLYOLEFINS EASTMAN CHEMICAL COMPANY (US) 1999-12-02 WO disclosed